Fighting Antibiotic Resistance: Insights Into Human Barriers and New Opportunities
Antibiotic resistance is a public health issue leading to the emergence of multi‐resistant bacteria. Human‐dependent factors are now driving the increase of resistance, notably through antibiotic misuse in human and animal health and environmental pollution.
Aubin Pitiot+3 more
wiley +1 more source
Neutrophil extracellular traps in cancer: From mechanisms to treatments
Neutrophil extracellular traps are intricately linked to the tumor microenvironment and play a crucial role in tumorigenesis, metastasis, and related complications. Consequently, NETs‐based tumor biomarkers and therapeutic strategies warrant significant attention.
Yifan Wang+5 more
wiley +1 more source
KSHV RTA Induces Degradation of the Host Transcription Repressor ID2 To Promote the Viral Lytic Cycle. [PDF]
Combs LR+4 more
europepmc +1 more source
Viral hijacking of cellular metabolism. [PDF]
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James+2 more
core
Human Herpesvirus 6 Activates Lytic Cycle Replication of Kaposi's Sarcoma-Associated Herpesvirus [PDF]
Chun Lu+6 more
openalex +1 more source
Supplementary Fig. S4C from Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase [PDF]
Jieying Zhong, Ying Chau
openalex +1 more source
ABSTRACT Tuberculosis (TB) is considered a major infectious disease by the World Health Organization. The WHO estimates that there are 1.8 million TB deaths, and 10.4 million new cases of the disease reported yearly. While there are conventional therapies for TB, they have drawbacks such as a lengthy pill regimen, rigorous scheduling, and protracted ...
Nnamdi Ikemefuna Okafor+3 more
wiley +1 more source
Kaposi's Sarcoma-Associated Herpesvirus Immediate Early Proteins Trigger FOXQ1 Expression in Oral Epithelial Cells, Engaging in a Novel Lytic Cycle-Sustaining Positive Feedback Loop. [PDF]
Atyeo N+4 more
europepmc +1 more source
Supplementary Fig. S4D from Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase [PDF]
Jieying Zhong, Ying Chau
openalex +1 more source
The Complex Role of CD8+ T Cells in Placental HIV Infection
CD8+ T cells exhibit dual roles at the maternal‐fetal interface supporting tolerance via IL‐10 and TGF‐β and aiding implantation and vascular remodeling through TNF‐α and IFN‐γ. In HIV infection, CD8+ T cells expand, driving inflammation, PD‐L1 upregulation on trophoblasts, and cytotoxic dysfunction via reduced Granzyme B and Perforin, compromising ...
Kimberly Peta+2 more
wiley +1 more source