Results 231 to 240 of about 100,112 (246)
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Epstein-Barr Virus Lytic Cycle Reactivation
2015Epstein-Barr virus, which mainly infects B cells and epithelial cells, has two modes of infection: latent and lytic. Epstein-Barr virus infection is predominantly latent; however, lytic infection is detected in healthy seropositive individuals and becomes more prominent in certain pathological conditions. Lytic infection is divided into several stages:
Ayman El-Guindy, Jessica McKenzie
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Lytic Cycle Switches of Oncogenic Human Gammaherpesviruses1
2007The seminal experiments of George and Eva Klein helped to define the two life cycles of Epstein-Barr Virus (EBV), namely latency and lytic or productive infection. Their laboratories described latent nuclear antigens expressed during latency and discovered several chemicals that activated the viral lytic cycle.
J. Countryman +4 more
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Genipin as a novel chemical activator of EBV lytic cycle
Journal of Microbiology, 2015Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that causes acute infection and establishes life-long latency. EBV causes several human cancers, including Burkitt's lymphoma, nasopharyngeal and gastric carcinoma. Antiviral agents can be categorized as virucides, antiviral chemotherapeutic agents, and immunomodulators.
Choon-Sik Jeong +9 more
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Switching of EBV cycles between latent and lytic states
Reviews in Medical Virology, 2013SUMMARYThe EBV is a human gamma‐herpesvirus that is associated with a variety of neoplasms. Upon primary infection, it transiently runs a short lytic program and then predominantly establishes latent infection. Only a small percentage of infected cells switch from the latent stage into the lytic cycle and produce progeny viruses. Although EBV in cancer
Tatsuya Tsurumi, Takayuki Murata
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An electron microscope study of the lytic cycle of Azotobacter bacteriophages
Soil Biology and Biochemistry, 1976Abstract The lytic cycle of two different Aztobacter bacteriophages was studied in ultrathin sections by means of electron microscopy. The latent period was found to be as long as 4–6 h. Detailed structural alterations in cells during the infection are reported and illustrated.
F. Ċiampor, Nabil A. Hegazi
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Induction of SV40 transplantation antigen (TrAg) during the lytic cycle
Virology, 1970Abstract Simian virus 40 transplantation antigen (SV40 TrAg) developed in a permissive cell system, African green monkey kidney (AGMK), after infection with active SV40. Hamsters that had received a tumor-inducing dose of SV40 at birth, followed by vaccination with infected AGMK or CV-1 cells during the latent period, were used as the test system for
Vittorio Defendi, Anthony J. Girardi
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Repression of ant synthesis early in the lytic cycle of phage P22
Molecular and General Genetics MGG, 1981Using SDS-polyacrylamide gel electrophoresis to study the early expression of P22 genes we show that early expression of the ant-gene (imm I region) is turned off after 6-8 min, independent of the 'late' acting mnt-repressor. A semi-clear mutant called cir5 is defective for this early ant turn-off.
H. H. Prell +4 more
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Inhibition of Epstein–Barr virus lytic cycle by (−)-epigallocatechin gallate
Biochemical and Biophysical Research Communications, 2003(-)-Epigallocatechin gallate (EGCG), abundant in green tea, is a potent anti-microbial and anti-tumor compound. This investigation used immunoblot, flow cytometry, microarray, and indirect immunofluorescence analyses to show that at concentrations exceeding 50 microM, EGCG inhibits the expression of Epstein-Barr virus (EBV) lytic proteins, including ...
Ta Tung Wei +7 more
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Simulated RNA Interference in the T4 Bacteriophage Lytic Cycle
2014RNA interference pathways have shown promise in disrupting the translation of protein products in eukaryotic cells and organisms. These studies have used siRNA or miRNA, but not mRNA. Bacteria lack the genes to produce the RNAi enzymes found in eukaryotes. In this study, an attempt to simulate an RNAi pathway in hopes of using E.
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Biological characterization of the lytic cycle of actinophage φA7 in Streptomyces antibioticus
FEMS Microbiology Letters, 1991Some basic parameters of the lytic development of phage phi A7 in Streptomyces antibioticus are described. One-step growth experiments demonstrated that at 28 degrees C phi A7 has a latent period of about 60 min and an exponential growth period of about 35 min. The average burst size ranged from 70-100 plaque forming units per infected cell.
Carlos Hardisson +3 more
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