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Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50/Rta Protein Activates the Entire Viral Lytic Cycle in the HH-B2 Primary Effusion Lymphoma Cell Line

open access: green, 2000
Lyndle Gradoville   +6 more
openalex   +2 more sources
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Epstein-Barr Virus Lytic Cycle Reactivation

2015
Epstein-Barr virus, which mainly infects B cells and epithelial cells, has two modes of infection: latent and lytic. Epstein-Barr virus infection is predominantly latent; however, lytic infection is detected in healthy seropositive individuals and becomes more prominent in certain pathological conditions. Lytic infection is divided into several stages:
Jessica, McKenzie, Ayman, El-Guindy
openaire   +2 more sources

Switching of EBV cycles between latent and lytic states

Reviews in Medical Virology, 2013
SUMMARYThe EBV is a human gamma‐herpesvirus that is associated with a variety of neoplasms. Upon primary infection, it transiently runs a short lytic program and then predominantly establishes latent infection. Only a small percentage of infected cells switch from the latent stage into the lytic cycle and produce progeny viruses. Although EBV in cancer
Takayuki, Murata, Tatsuya, Tsurumi
openaire   +2 more sources

Formation of mRNP granules in Toxoplasma gondii during the lytic cycle

Molecular and Biochemical Parasitology, 2021
Two poly(A) binding proteins (PABPs) of Toxoplasma gondii, were identified and characterized. They were named TgPABPC and TgPABPN as they were found to localize in the cytoplasm and nucleus respectively. TgPABPC, which colocalizes with mRNA granules, is therefore used as a cellular marker of mRNP granules.
Scott Roscoe   +3 more
openaire   +2 more sources

Induction of SV40 transplantation antigen (TrAg) during the lytic cycle

Virology, 1970
Abstract Simian virus 40 transplantation antigen (SV40 TrAg) developed in a permissive cell system, African green monkey kidney (AGMK), after infection with active SV40. Hamsters that had received a tumor-inducing dose of SV40 at birth, followed by vaccination with infected AGMK or CV-1 cells during the latent period, were used as the test system for
A J, Girardi, V, Defendi
openaire   +2 more sources

Genipin as a novel chemical activator of EBV lytic cycle

Journal of Microbiology, 2015
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that causes acute infection and establishes life-long latency. EBV causes several human cancers, including Burkitt's lymphoma, nasopharyngeal and gastric carcinoma. Antiviral agents can be categorized as virucides, antiviral chemotherapeutic agents, and immunomodulators.
Myoungki, Son   +9 more
openaire   +2 more sources

Inhibition of Epstein–Barr virus lytic cycle by (−)-epigallocatechin gallate

Biochemical and Biophysical Research Communications, 2003
(-)-Epigallocatechin gallate (EGCG), abundant in green tea, is a potent anti-microbial and anti-tumor compound. This investigation used immunoblot, flow cytometry, microarray, and indirect immunofluorescence analyses to show that at concentrations exceeding 50 microM, EGCG inhibits the expression of Epstein-Barr virus (EBV) lytic proteins, including ...
Li-Kwan, Chang   +7 more
openaire   +2 more sources

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