Results 71 to 80 of about 2,996,356 (190)
Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor.
Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG-containing DNA response elements in a methylation-dependent manner.
Kirsty Flower+5 more
doaj +1 more source
Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta [PDF]
The human gamma herpes virus Epstein–Barr virus (EBV) exploits multiple routes to evade the cellular immune response. During the EBV lytic replication cycle, viral proteins are expressed that provide excellent targets for recognition by cytotoxic T cells.
Alison J. Sinclair+17 more
core +3 more sources
Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An Update
The life cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) consists of two phases, latent and lytic. The virus establishes latency as a strategy for avoiding host immune surveillance and fusing symbiotically with the host for lifetime persistent ...
Yan Yuan, Kawalpreet K. Aneja
doaj +1 more source
From DNA sequence to application: possibilities and complications [PDF]
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin+110 more
core +3 more sources
The cytolytic T lymphocyte response to the murine cytomegalovirus [PDF]
During the acute cytolytic T lymphocyte (CTL) response of mice to infection with the murine cytomegalovirus two independent populations of activated interleukin-receptive CTL precursors can be demonstrated.
Ada+25 more
core +1 more source
Background EBV lytic cycle activators, such as phorbol esters, anti-immunoglobulin, transforming growth factor β (TGFβ), sodium butyrate, induce apoptosis in EBV-negative but not in EBV-positive Burkitt's lymphoma (BL) cells. To investigate the molecular
Di Renzo Livia+4 more
doaj +1 more source
The motility of a human parasite, Toxoplasma gondii, is regulated by a novel lysine methyltransferase. [PDF]
Protozoa in the phylum Apicomplexa are a large group of obligate intracellular parasites. Toxoplasma gondii and other apicomplexan parasites, such as Plasmodium falciparum, cause diseases by reiterating their lytic cycle, comprising host cell invasion ...
Aoife T Heaslip+3 more
doaj +1 more source
Toxoplasma gondii is a widespread protozoan parasite infecting nearly all warm-blooded organisms. Asexual reproduction of the parasite within its host cells is achieved by consecutive lytic cycles, which necessitates biogenesis of significant energy and ...
Richard Nitzsche+3 more
semanticscholar +1 more source
Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency.
Herpesviruses establish a lifelong latent infection posing the risk for virus reactivation and disease. In cytomegalovirus infection, expression of the major immediate early (IE) genes is a critical checkpoint, driving the lytic replication cycle upon ...
Franziska Dağ+17 more
doaj +1 more source
Calcium Signaling throughout the Toxoplasma gondii Lytic Cycle
Background: Ca2+ signaling is important for the lytic cycle of T. gondii. Results: Genetically encoded Ca2+ indicators revealed cytosolic Ca2+ changes in real time. Conclusion: New approach highlights important features of the lytic cycle.
Lucas Borges-Pereira+9 more
semanticscholar +1 more source