Results 81 to 90 of about 100,112 (246)
Antiviral effects and mechanism of Qi pi pill against influenza viruses
Animal Models and Experimental Medicine, EarlyView.Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang +10 more
wiley +1 more source
Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor.
PLoS ONE, 2011 Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG-containing DNA response elements in a methylation-dependent manner.
Kirsty Flower +5 more
doaj +1 more source
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]
, 2017 The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core +1 more source
Animal Models and Experimental Medicine, EarlyView.To compensate for the fluorescence loss in rabies virus–derived neuronal tracing tools caused by non‐cytolytic immune clearance (NCLIC) in retrograde tracing, we developed a novel green‐to‐red spectral labeling (GTR) strategy based on the NCLIC phenomenon and developed a novel marker footprints mouse to support the strategy.
Yige Song +4 more
wiley +1 more source
Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An Update
Frontiers in Microbiology, 2017 The life cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) consists of two phases, latent and lytic. The virus establishes latency as a strategy for avoiding host immune surveillance and fusing symbiotically with the host for lifetime persistent ...
Yan Yuan, Kawalpreet K. Aneja
doaj +1 more source
Telomeres in Evolution and Development from Biosemiotic Perspective [PDF]
, 2007 Telomeres identify natural chromosome ends being different from broken DNA through differences in their "molecular syntax" (M.Eigen) which determines the functions of reverse transcriptase and its integrated RNA template, telomerase.
Guenther Witzany
core +3 more sources
Toxoplasma gondii F-actin forms an extensive filamentous network required for material exchange and parasite maturation [PDF]
, 2017 Apicomplexan actin is important during the parasite's life cycle. Its polymerization kinetics are unusual, permitting only short, unstable F-actin filaments.
Abounit +53 more
core +2 more sources
Molecular Cancer, 2009 Background EBV lytic cycle activators, such as phorbol esters, anti-immunoglobulin, transforming growth factor β (TGFβ), sodium butyrate, induce apoptosis in EBV-negative but not in EBV-positive Burkitt's lymphoma (BL) cells. To investigate the molecular
Di Renzo Livia +4 more
doaj +1 more source
The motility of a human parasite, Toxoplasma gondii, is regulated by a novel lysine methyltransferase. [PDF]
PLoS Pathogens, 2011 Protozoa in the phylum Apicomplexa are a large group of obligate intracellular parasites. Toxoplasma gondii and other apicomplexan parasites, such as Plasmodium falciparum, cause diseases by reiterating their lytic cycle, comprising host cell invasion ...
Aoife T Heaslip +3 more
doaj +1 more source
Complexities associated with expression of Epstein-Barr virus (EBV) lytic origins of DNA replication. [PDF]
, 2007 EBV has two lytic origins (oriLyt) of DNA replication lying at divergent sites on the viral genome within a duplicated sequence (DS). The latter contains potential hairpin loops, ‘hinge’ elements and the promoters for transcripts from viral genes BHLF1 ...
Griffin, BE, Xue, SA
core +2 more sources