Recent advances in the efficient degradation of lignocellulosic metabolic networks by lytic polysaccharide monooxygenase [PDF]
Acta Biochimica et Biophysica Sinica, 2023 Along with long-term evolution, the plant cell wall generates lignocellulose and other anti-degradation barriers to confront hydrolysis by fungi. Lytic polysaccharide monooxygenase (LPMO) is a newly defined oxidase in lignocellulosic degradation systems ...
Yu Xinran +3 more
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A Novel Lytic Polysaccharide Monooxygenase From Enrichment Microbiota and Its Application for Shrimp Shell Powder Biodegradation [PDF]
Frontiers in Microbiology, 2023 Lytic polysaccharide monooxygenases (LPMO) are expected to change the current status of chitin resource utilization. This study reports that targeted enrichment of the microbiota was performed with chitin by the selective gradient culture technique, and ...
Delong Pan, Xiuling Zhou, Qianqian Xu
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Lytic polysaccharide monooxygenase synergized with lignin-degrading enzymes for efficient lignin degradation [PDF]
iScience, 2023 Summary: Even though the discovery of lytic polysaccharide monooxygenases (LPMOs) has fundamentally shifted our understanding of biomass degradation, most of the current studies focused on their roles in carbohydrate oxidation.
Su Sun +12 more
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Investigating lytic polysaccharide monooxygenase-assisted wood cell wall degradation with microsensors [PDF]
Nature Communications, 2022 It is important to understand the enzymatic degradation of wood biomass by lytic polysaccharide monooxygenase, however, disagreements about the co-substrate exist. Here, the authors use piezo-controlled hydrogen peroxide micro-sensors to demonstrate that
Hucheng Chang +7 more
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Role for a Lytic Polysaccharide Monooxygenase in Cell Wall Remodeling in Streptomyces coelicolor [PDF]
mBio, 2022 Peptidoglycan is a major constituent of the bacterial cell wall and an important determinant for providing protection to cells. In addition to peptidoglycan, many bacteria synthesize other glycans that become part of the cell wall.
Xiaobo Zhong +4 more
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Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase [PDF]
FEBS Open BioThe genome of Fusarium solani, a well‐known plant pathogen, encodes various lytic polysaccharide monooxygenases (LPMOs) involved in plant biomass degradation in combination with cellobiose dehydrogenase (CDH).
Angela Giorgianni +4 more
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Inhibition of the Peroxygenase Lytic Polysaccharide Monooxygenase by Carboxylic Acids and Amino Acids [PDF]
Antioxidants, 2022 Lytic polysaccharide monooxygenases (LPMOs) are widely distributed in fungi, and catalyze the oxidative degradation of polysaccharides such as cellulose.
Erik Breslmayr +6 more
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Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates [PDF]
Scientific Reports, 2023 Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that use O2 or H2O2 to oxidatively cleave glycosidic bonds. LPMOs are prevalent in nature, and the functional variation among these enzymes is a topic of great interest.
Heidi Østby +9 more
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Mutational dissection of a hole hopping route in a lytic polysaccharide monooxygenase (LPMO) [PDF]
Nature CommunicationsOxidoreductases have evolved tyrosine/tryptophan pathways that channel highly oxidizing holes away from the active site to avoid damage. Here we dissect such a pathway in a bacterial LPMO, member of a widespread family of C-H bond activating enzymes with
Iván Ayuso-Fernández +12 more
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Heterologous expression and characterization of novel GH12 β-glucanase and AA10 lytic polysaccharide monooxygenase from Streptomyces megaspores and their synergistic action in cellulose saccharification [PDF]
Biotechnology for Biofuels and Bioproducts, 2023 Background The combination of cellulase and lytic polysaccharide monooxygenase (LPMO) is known to boost enzymatic saccharification of cellulose. Although the synergy between cellulases (GH5, 6 or 7) and LPMOs (AA9) has been extensively studied, the ...
Xing Qin +9 more
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