Results 81 to 90 of about 568,996 (254)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A literature review highlights the evolution of studies about the strategy of small and medium enterprises (SME) and points out some research needs. Studies on the traditional perspective of the subject (which is prescriptive and based on design, formal planning and positioning) are included as well as contributions and limitations.
openaire +1 more source
International audienceL'objectif de cette communication serait effectivement de s'interroger voire d'analyser les causes de la pérennité de certains acteurs et la disparition des autres.
Amamou, Leila
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Représentations de la mort dans les médias d'information [PDF]
Malgré l'omniprésence de la mort dans les colonnes de la presse ou sur les écrans de télévision, le sujet reste très peu abordé par les analystes des médias, comme si le " tabou " qui entoure la mort se propageait jusqu'au domaine de l'analyse.
Florea, Marie-Laure, Rabatel, Alain
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
« L’anthropo_scenes » : les mèmes au service des intérêts des animaux
Ce texte revient sur une expérimentation pédagogique menée avec des étudiant·es de master, portant sur la création de contenus numériques dans une page Instagram intitulée « L’anthropo_scenes ». Elle est consacrée à la création des mèmes sur les animaux,
Nataly Botero
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

