The STEMRI trial: Magnetic resonance spectroscopy imaging can define tumor areas enriched in glioblastoma stem-like cells. [PDF]
Lemarié A +13 more
europepmc +1 more source
The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery +17 more
wiley +1 more source
[The role of histopathology in the diagnosis and management of intracranial meningiomas. Hospital experience in Kinshasa (Democratic Republic of Congo)]. [PDF]
Kapiamba EN +5 more
europepmc +1 more source
ABSTRACT Moderately hypofractionated definitive‐intent radiotherapy protocols can be used for canine intracranial meningiomas to shorten overall treatment time while maintaining tumour control and limiting normal tissue toxicity. This retrospective study evaluated oncologic outcomes, toxicity, and radiation dose‐volume‐related prognostic factors in ...
Carlotta Ahrens +2 more
wiley +1 more source
Molecular signature of brain metastases [PDF]
Au cours des vingt dernières années, l'incidence des métastases cérébrales a augmenté. Malgré les progrès thérapeutiques, le pronostic des métastases cérébrales reste sombre, avec une médiane de survie de moins de 16 mois.
Nguyen, Thi Thuy
core
Exploratory Gene Expression Profiling of Cisplatin-Induced Neurotoxicity in Rat Brain. [PDF]
Torres-Pineda O +6 more
europepmc +1 more source
PEA3 Transcription Factors, Role in Invasion, Proliferation and Radioresistance of Glioblastoma Stem Cells. [PDF]
Nicaise Y +3 more
europepmc +1 more source
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Brain tumoroids: Treatment prediction and drug development for brain tumors with fast, reproducible, and easy-to-use personalized models. [PDF]
Soubéran A +12 more
europepmc +1 more source
Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale +17 more
wiley +1 more source

