Results 131 to 140 of about 18,955 (175)

Évaluation de l'efficacité de la radiochirurgie dans le traitement des métastases cérébrales de plus de 10 cm3

, 2019
L'objectif de l'étude est d'évaluer l'efficacité et la toxicité de la radiochirurgie fractionnée dans le traitement des métastases cérébrales de plus de 10 cm3. Nous avons réalisé une étude rétrospective, monocentrique, au CHU d'Amiens, de septembre 2016
Bunaux, Katia
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, Volume 13, Issue 63, 12 November 2026.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

[Clinical And Therapeutic Characteristics Of Gestational Trophoblastic Tumors In The Point G's University Hospital]. [PDF]

Mali Med
Sidibé FM, Kéita S, Diallo M, Sima M, Sidibé A, Bathily M, Samaké CO, Saye Z, Koné AA, Doumbia HD, Diallo H, Sidibé S.   +11 more
europepmc   +1 more source

The STEMRI trial: Magnetic resonance spectroscopy imaging can define tumor areas enriched in glioblastoma stem-like cells. [PDF]

Sci Adv, 2023
Lemarié A, Lubrano V, Delmas C, Lusque A, Cerapio JP, Perrier M, Siegfried A, Arnauduc F, Nicaise Y, Dahan P, Filleron T, Mounier M, Toulas C, Cohen-Jonathan Moyal E.   +13 more
europepmc   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, Volume 13, Issue 62, 9 November 2026.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

[The role of histopathology in the diagnosis and management of intracranial meningiomas. Hospital experience in Kinshasa (Democratic Republic of Congo)]. [PDF]

Med Trop Sante Int
Kapiamba EN, Mikuo OK, Eba GN, Mpolesha JK, Massamba BL, Bulakali RC.   +5 more
europepmc   +1 more source

Apport diagnostique des séquences IRM de diffusion, perfusion et spectroscopie dans le bilan initial des tumeurs cérébrales intra-axiales de l'adulte

, 2011
L'objectif est de définir l'intérêt diagnostique des séquences IRM de diffusion, de perfusion et de spectroscopie dans le bilan initial des tumeurs cérébrales intra-axiales de l'adulte. 57 patients ont été inclus de novembre 2009 à octobre 2010.
CLAISE, Béatrice, CAMARA, Pierre-Yves
core  

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3902-3913, November 2026.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Exploratory Gene Expression Profiling of Cisplatin-Induced Neurotoxicity in Rat Brain. [PDF]

Int J Mol Sci
Torres-Pineda O, Morgado-Valle C, Chi-Castañeda D, López-Meraz ML, Rodríguez-Razón CM, Macías-Carballo M, Beltrán-Parrazal L.   +6 more
europepmc   +1 more source

Intraosseous Angiolipoma of the Maxilla: First Reported Case With a Review of the Literature

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Angiolipomas are benign mesenchymal neoplasms composed of mature adipocytes and vascular channels, typically occurring in subcutaneous tissue. Intraosseous is extremely rare and has been described in only 22 cases in the previous studies, affecting mainly the mandible, calvarium, ribs, and long bones.
Shervin Shafiei, Armin Khaleghi, Hamidreza Arefifard, Nafise Shamloo   +3 more
wiley   +1 more source