Results 111 to 120 of about 7,053,740 (251)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Enrique Dussel and Liberation Theology: Violence or Dialogue? [PDF]
, 2014 For centuries, several disciplines have tried to tackle the topic of how legitimate it is to use violence in order to solve social problems. One of the most recent interdisciplinary approaches (and one of the most successful in present-day Latin America)
Paz, Miguel Ángel Quintana
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Comportamiento del resultado de las Bandas oligoclonales en líquidocefalorraquídeo en Pacientes con esclerosis múltiple del Hospital Militar Centra [PDF]
, 2013 La esclerosis múltiple es la enfermedad neurológica más común y discapacitante en adultos jóvenes1 en Colombia se estima una prevalencia de 1,48 a 4,98 casos por 100.000 habitantes.
Cabrera Limpias, Sergio +1 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
El punt de vista en la narrativa: el desenrotllament d'un concepte crític / [PDF]
, 1975 Repàs als diversos punts de vista: l'omnisciència editorial, l'omnisciència neutral, el "jo" com a testimoni, el "jo" com a protagonista, l'omnisciència múltiple i ...
Friedman, Norman
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Empoderamiento y proactividad ante la Esclerosis Múltiple
Revista Española de Discapacidad, 2013 Esclerosis Múltiple España (2013): “Empoderamiento y proactividad ante la Esclerosis Múltiple”, Revista Española de Discapacidad, 1 (1): 225-231.
Esclerosis Múltiple España
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