Results 141 to 150 of about 12,489,240 (294)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Esclerosis múltiple, una enfermedad desmielinizante [PDF]

open access: yes, 2017
La esclerosis múltiple es una enfermedad desmielinizante del sistema nervioso central, que suele comenzar en adultos de entre 20 y 40 años de edad. La susceptibilidad genética unido a factores ambientales contribuyen a una alteración del sistema inmune ...
Rebollo Quintero, Juan José
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Nou mètode per tractar els brots d'esclerosi múltiple [PDF]

open access: yes, 2013
Investigadors del Servei de Neurologia de l'Hospital Germans Trias i Pujol de Badalona han elaborat un nou protocol per tractar els brots d'esclerosi múltiple. Aquest protocol classifica els brots en lleus, moderats o greus, segons la puntuació obtinguda
Ramo Tello, Cristina   +1 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Técnicas de ARQ en un esquema de acceso por paquetes DS-CDMA [PDF]

open access: yes, 1998
Peer ReviewedPostprint (published ...
Agustí Comes, Ramon   +2 more
core  

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