Results 31 to 40 of about 7,053,740 (251)

Esclerosis múltiple: últimos avances [PDF]

open access: yes, 2018
La esclerosis múltiple (EM) es una enfermedad autoinmune y degenerativa que destruye la mielina de las neuronas del Sistema Nervioso Central (SNC).
González Rodríguez, Marta
core  

An Autonomous Engine for Services Configuration and Deployment.

open access: yes, 2011
The runtime management of the infrastructure providing service-based systems is a complex task, up to the point where manual operation struggles to be cost effective. As the functionality is provided by a set of dynamically composed distributed services,
Cuadrado Latasa, Felix   +2 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Esclerosis múltiple, una enfermedad desmielinizante [PDF]

open access: yes, 2017
La esclerosis múltiple es una enfermedad desmielinizante del sistema nervioso central, que suele comenzar en adultos de entre 20 y 40 años de edad. La susceptibilidad genética unido a factores ambientales contribuyen a una alteración del sistema inmune ...
Rebollo Quintero, Juan José
core  

Robust 3D People Tracking and Positioning System in a Semi-Overlapped Multi-Camera Environment [PDF]

open access: yes, 2008
People positioning and tracking in 3D indoor environments are challenging tasks due to background clutter and occlusions. Current works are focused on solving people occlusions in low-cluttered backgrounds, but fail in high-cluttered scenarios, specially
Blanco Adán, Carlos Roberto del   +4 more
core   +2 more sources

Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis

open access: yesFrontiers in Immunology, 2019
Gut microbiota dysbiosis has been implicated in MS and other immune diseases, although it remains unclear how manipulating the gut microbiota may affect the disease course.
Leyre Mestre   +15 more
doaj   +1 more source

A Polymorphism Within the MBP Gene Is Associated With a Higher Relapse Number in Male Patients of Multiple Sclerosis

open access: yesFrontiers in Immunology, 2020
Myelin basic protein (MBP) is thought to be one of the key autoantigens in multiple sclerosis (MS) development. A recent study described the association of the single nucleotide polymorphism (SNP) rs12959006, within the MBP gene, with a higher risk of ...
Laura Espino-Paisán   +10 more
doaj   +1 more source

Nuevas perspectivas textuales: modalidades híbridas e hipertexualidad [PDF]

open access: yes, 2018
La hibridación, la interferencia y la interrupción significativa del relato son los procedimientos estéticos que dan una respuesta más adecuada a la pluralidad de narrativas de múltiple procedencia, con el resultado de una narrativa hipertextual ...
Velasco-Rengel, Carmen
core  

Design and evaluation of acceleration strategies for speeding up the development of dialog applications [PDF]

open access: yes, 2011
In this paper, we describe a complete development platform that features different innovative acceleration strategies, not included in any other current platform, that simplify and speed up the definition of the different elements required to design a ...
Agah   +14 more
core   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

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