IFN-γ +874 T/A Is Associated with High Levels of Sera CPK in Patients with Inflammatory Myopathies [PDF]
Current Issues in Molecular BiologyAim of the study: Idiopathic inflammatory myopathies (IIM) are autoimmune diseases with a low prevalence and incidence worldwide. The levels of IFN-γ production by T-lymphocytes are related to disease activity.
Mónica Vázquez-Del Mercado +3 more
doaj +2 more sources
Cardiovascular risk scores, non-invasive vascular measures and myositis damage index reveal increased cardiovascular risk in idiopathic inflammatory myopathies: a case-control study [PDF]
BMC RheumatologyBackground Data about cardiovascular risk (CVR) in idiopathic inflammatory myopathies (IIM) may not be fully captured by traditional scores. This case-control study evaluated cardiovascular disease (CVD) risk through non-invasive tools in IIM patients ...
Gabriela Paola Garcia-Ordoñez +8 more
doaj +2 more sources
Preliminary ultrastructural analysis suggests phenotype-specific myofiber alterations in idiopathic inflammatory myopathies [PDF]
Scientific ReportsIdiopathic inflammatory myopathies (IIM) comprise a heterogeneous group of autoimmune muscle diseases with variable patterns of muscle damage. In this multicentric cross-sectional study, we employed scanning electron microscopy (SEM) to characterize ...
Andrea Aguilar-Vazquez +24 more
doaj +2 more sources
Treinamento Físico Reduz a Inflamação e a Fibrose e Preserva a Função e a Perfusão Miocárdica em um Modelo de Cardiomiopatia Chagásica Crônica [PDF]
Arquivos Brasileiros de CardiologiaResumo Fundamento: A Cardiomiopatia Chagásica Crônica (CCC) é causada por um processo inflamatório induzido pelo Trypanosoma cruzi, que leva à miocardite com fibrose reativa e reparativa.
Thayrine R. Damasceno +14 more
doaj +2 more sources
Impaired muscle strength is associated with ultrastructure damage in myositis
Scientific Reports, 2022 The muscle fiber ultrastructure in Idiopathic Inflammatory Myopathies (IIM) has been scarcely explored, especially in Inclusion Body Myositis. The aim of this study was to implement the Scanning Electron Microscopy (SEM) in a small cohort of IIM patients,
Andrea Aguilar-Vazquez +20 more
doaj +1 more source
Biomolecules, 2023 Osteopontin (OPN) is a bone-derived phosphoglycoprotein related to physiological and pathological mechanisms that nowadays has gained relevance due to its role in the immune system response to chronic degenerative diseases, including rheumatoid arthritis
Beatriz Teresita Martín-Márquez +8 more
doaj +1 more source
Scientific Reports, 2023 YKL-40 increase according to the aging process, and its functions have been associated with tissue remodeling and systemic inflammation. In Rheumatoid Arthritis (RA) it has been proposed as a possible biomarker of activity and severity, however; in the ...
Mónica Vázquez-Del Mercado +12 more
doaj +1 more source
Poder del músculo esquelético en la salud y enfermedad
Revista de Nutrición Clínica y Metabolismo, 2021 Las evidencias científicas son contundentes en mostrar que la inactividad física y el comportamiento sedentario tienen efectos perjudiciales en el músculo esquelético, las arterias, el miocardio y las mitocondrias, lo que aumenta el riesgo de ...
Sandra Marcela Mahecha
doaj +1 more source
Estudo histomorfométrico do músculo esquelético de ratos em anestro [PDF]
Acta Cirúrgica Brasileira, 2005 A castração, assim como a menopausa, representa estágio de supressão endócrina em que prevalece o hipoestrogenismo e sua conseqüência maior sobre o músculo esquelético é provocar sarcopenia.
Manoel de Almeida Moreira +3 more
doaj +1 more source
Influence of aerobic physical training in the motochondrial transport of long chain fatty acids in the skeletal muscle: role of the carnitine palmitoil transferase [PDF]
, 2008 O ácido graxo (AG) é uma importante fonte de energia para o músculo esquelético. Durante o exercício sua mobilização é aumentada para suprir as necessidades da musculatura ativa.
CARNEVALI JR., Luiz Carlos +6 more
core +2 more sources