Results 131 to 140 of about 111,163 (223)

Urea cycle modulation by combined SGLT2 inhibitors and metformin. [PDF]

BMC Med
Harada M, Adam J, Han S, Shi M, Ge J, Lintelmann J, Cecil A, Zukunft S, Prehn C, Witting M, Scheerer MF, Neschen S, Irmler M, Beckers J, Adamski J, Teupser D, Linkohr B, Gieger C, de Angelis MH, Peters A, Wang-Sattler R.   +20 more
europepmc   +1 more source

Exploring dietary adaptations in Ursus minimus: a 3D geometric morphometric analysis of the mandible

Boreas, EarlyView.
Using 3D geometric morphometrics, the dietary adaptations of the extinct Auvergne bear (Ursus minimus) are analysed. Its mandibular morphology aligns more closely with omnivorous rather than insectivorous bears, challenging current ideas. The extinct bear Ursus minimus, which lived in Europe during the Pliocene and possibly Early Pleistocene, is ...
Anneke H. van Heteren
wiley   +1 more source

[Assisted suicide: assessment and evaluation of the ability to make a freely responsible decision]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Nedopil N, Brieger P.
europepmc   +1 more source

Fossil bears break free from inhibitory cascade constraints at least twice (Ursus minimus and Ursus deningeri) caused by dietary adaptations

Boreas, EarlyView.
Bears deviate from the inhibitory cascade model (ICM) during molar size evolution, with two significant deviations linked to changes in diet: Ursus minimus and Ursus deningeri. Many bears exhibit a ‘partial ICM’, highlighting the relationship between relative molar size, dietary adaptations and dental development across different species.
Anneke H. van Heteren, A. Stefanie Luft
wiley   +1 more source

Association of DNA methylation with hypertension and blood pressure: a 7-year longitudinal study from KORA F4/FF4. [PDF]

BMC Med
Lai L, Jong ASY, Delerue T, Lin J, Thorand B, Heier M, Prokisch H, Farzeen A, Winkelmann J, Thiering E, Gieger C, Peters A, Waldenberger M.   +12 more
europepmc   +1 more source

Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity

British Journal of Pharmacology, EarlyView.
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand, Simone Brogi, Mustafa Tezeren, Andrea Tafi, Omer H. Ocak, Hasan Koyuncu, Igor Tetko, Laurent Désaubry, Canan G. Nebigil   +8 more
wiley   +1 more source

Harnessing Digital Pathology Tools to Distinguish Hand Eczema From Palmar Psoriasis: A Quantitative Approach

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinguishing hand eczema from palmar psoriasis is a common diagnostic challenge due to overlapping clinical and histopathological features. Objective This study aimed to validate morphological and immunohistochemical criteria for differentiating these two conditions using the digital pathology tools QuPath and ImageJ.
Melissa Sari, Stefan Schliep, Anne Petzold, Franklin Kiesewetter, Michael Erdmann, Michael Sticherling, Carola Berking, Markus V. Heppt, Elias A. T. Koch   +8 more
wiley   +1 more source

Evidence of ascariasis in a Celtic newborn from northern Italy. [PDF]

Mem Inst Oswaldo Cruz
López-Gijón R, Teegen WR, Laffranchi Z, Vitali D, Zink A, Milella M.   +5 more
europepmc   +1 more source

From narratives to numbers and back: Assessing the psychosocial aspects of diabetes in the era of high technology with emerging qualitative and quantitative methodologies

Diabetic Medicine, EarlyView.
Abstract Aims Rapid changes in diabetes therapy combined with limitations of traditional methodological approaches challenge the field of psychosocial research to adequately capture the experiences of people with diabetes. This narrative review provides an overview of emerging qualitative and quantitative approaches that can advance the study of ...
Dominic Ehrmann, Eloise Litterbach, Sonya Deschenes, Rita Forde, Norbert Hermanns, Maaike Horsselenberg, Mandy Jansen, Amy McInerney, Eimear Morrissey, Andreas Schmitt, Uffe Søholm, Giesje Nefs   +11 more
wiley   +1 more source

[Assisted suicides in Bavaria from 2020 to 2023-the first results from the multiple cause of death statistics]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Buschner A, Gleich S, Schäffer B.
europepmc   +1 more source