Embryo transfer following IVF alters susceptibility to metabolic phenotypes in male mouse offspring compared to naturally conceived offspring. [PDF]
Laurent K +7 more
europepmc +1 more source
Abstract Introduction Insulin autoantibodies (IAA) are key predictors of type 1 diabetes, particularly in young children. Micro‐radiobinding assays (RBA) are the gold standard for IAA measurement but have limitations. We assessed whether a luciferase immunoprecipitation system (LIPS) assay improved diabetes risk assessment.
Rebecca C. Wyatt +38 more
wiley +1 more source
Cardiac disease in patients with inflammatory myopathy. [PDF]
Binzenhöfer L +6 more
europepmc +1 more source
ABSTRACT Aims Treatment options for metabolic dysfunction‐associated steatotic liver disease (MASLD) are limited. While glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) and sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors improve cardiovascular outcomes, comparative effectiveness on liver‐related outcomes remains unclear.
Gregor A. Maier +4 more
wiley +1 more source
A new species and record of <i>Xestochironomus</i> Sublette & Wirth, 1972 (Diptera, Chironomidae) from the Dominican Republic, with males and females associated by DNA barcode. [PDF]
Fusari LM +3 more
europepmc +1 more source
Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer +6 more
wiley +1 more source
Kaufhaus Schottländer München-Rotkreuzplatz, Naundorf, München
KAUFHAUS SCHOTTLÄNDER MÜNCHEN-ROTKREUZPLATZ, NAUNDORF, MÜNCHEN Kaufhaus Schottländer München-Rotkreuzplatz, Naundorf, München ( -
Kaufhaus Schottländer +1 more
core
Upward Air Temperature Shifts and Acute Cardiovascular Events in Individuals with Atherosclerotic Cardiovascular Disease: A Time-Stratified Case-Crossover Study. [PDF]
Lechner K +14 more
europepmc +1 more source
Fast & fuelious: the malate–aspartate shuttle in brown adipocyte lipid metabolism
Brown adipose tissue (BAT) produces heat in response to cold exposure, for which it relies on the coordination of aerobic and anaerobic metabolism. However, how reaction intermediates connect these two essential pathways is unclear. In this issue of The FEBS Journal, Veliova et al., report that the malate–aspartate shuttle (MAS) supports norepinephrine‐
Lukas Blaas, Alexander Bartelt
wiley +1 more source

