Results 141 to 150 of about 32,229,416 (193)

A new functional assay reveals that membrane binding is critical for overactivation of the phosphoinositide 3-kinase H1047R mutant. [PDF]

open access: yesJ Biol Chem
Papafotika A   +10 more
europepmc   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

open access: yesSmall, Volume 22, Issue 43, 3 August 2026.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

open access: yesSmall, Volume 22, Issue 46, 18 August 2026.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem   +12 more
wiley   +1 more source

The fusion subunit vaccine L-DBF protects aged mice against heterologous lethal <i>Shigella</i> challenge after prior exposure. [PDF]

open access: yesFront Immunol
Parvej MS   +9 more
europepmc   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, Volume 26, Issue 8, August 2026.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

Substrate‐specific mitochondrial dysfunction and metabolomic profiles in type 2 diabetic rat hearts

open access: yesExperimental Physiology, Volume 111, Issue 8, Page 3635-3647, 1 August 2026.
Abstract Type 2 diabetes (T2D) greatly alters cardiac fuel handling, yet how mitochondrial function adapts to the diabetic substrate environment remains unclear. This study investigated substrate‐specific cardiac mitochondrial bioenergetics from a T2D rat model induced by a high‐fat diet and low‐dose streptozotocin.
Toan Pham
wiley   +1 more source

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