Results 81 to 90 of about 32,229,416 (193)

A photoimmune synergizing RNA interference technology for highly effective antitumor treatment

Smart Molecules, EarlyView.
We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia, Bingbing Wu, Xueze Zhao, Wen Sun, Jianjun Du, Jiangli Fan, Xiaojun Peng   +6 more
wiley   +1 more source

Mapping of C5‐Blocking Monoclonal Antibodies Reveals New C5 Inhibitory Epitopes and Novel Modes of C5 Inhibition

Immunology, EarlyView.
We identify four distinct C5 inhibitory epitopes, including two novel antibodies that selectively block membrane attack complex (MAC) assembly while preserving C5 cleavage and C5a generation. These findings establish selective MAC inhibition as a new therapeutic strategy for complement‐mediated diseases.
Rebekah Sian Cooke, Kok Yung Lee, Georgina Elizabeth Menzies, Masashi Mizuno, Bryan Paul Morgan, Wioleta Milena Zelek   +5 more
wiley   +1 more source

Otel işletmelerinde psikolojik dayanıklılık ve yöneticilerin adalet algıları arasındaki ilişki üzerine bir araştırma [PDF]

, 2017
Bu çalışmanın amacı, otel işletmelerindeki yöneticilerin psikolojik dayanıklılık ile örgütsel adalet algıları arasındaki ilişkiyi belirlemektir. Luthans ve arkadaşları (2007) tarafından Pozitif Psikolojik Sermaye Ölçeğinin alt ölçeği olan Psikolojik ...
Kırtulukoğlu Acar, Esra, İslamoğlu, Ebrucan   +1 more
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Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

[Report to W. P. Gannaway by P. M. Parks, February 10, 1964 #2] [PDF]

, 1964
Intelligence report addressed to W. P. Gannaway of the Dallas Police Department's Special Service Bureau. The report, which was submitted by detective P. M. Parks, states that Brenda Ray is married to W. G.
Dallas (Tex.). Police Department.
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A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

Study on Diphenylamine Oxidation by Ozone Using Atmospheric Pressure Chemical Ionization Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.
ABSTRACT Rationale Diphenylamine (DPAH) derivatives, widely used as antioxidants, interact with oxygen molecules (or ozone) to form radicals at the amine group. Although the antioxidation mechanism involves radical processes, separating these radicals using chromatography is challenging. Methods Rapid oxidation of DPAH was achieved through ozonation in
Eunji Chae, Chae Eun Son, Sung‐Seen Choi   +2 more
wiley   +1 more source

A Stable Hemicarceplex With an Encapsulated Cationic Guest

Journal of Physical Organic Chemistry, Volume 39, Issue 10, October 2026.
A hemicarcerplex with cobaltocenium ion on the inside and hexafluorophosphate on the outside was synthesized, and both it and its empty hemicarcerand precursor were characterized by X‐ray crystallography. The encapsulation equilibrium constant was also measured, and M06‐2X/cc‐pVDZ model computations are reported. ABSTRACT A hemicarcerand first reported
Casey Lee‐Foss, Alex Lovstedt, Lewis Nguyen, Steven R. Kass   +3 more
wiley   +1 more source

[Report to W. P. Gannaway by P. M. Parks and M. H. Brumley, February 17, 1964 #4] [PDF]

, 1964
Intelligence Report by P. M. Parks to Captain W. P. Gannaway, through Lieutenant Jack Revill. The report is concerning statements from Eddie Piper, an employee of the Texas School Book Depository.
Parks, P. M.
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Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco, M. Rusconi, J. Saglietto, P. Renzi, A. Deagostino, E. Azzi   +5 more
wiley   +1 more source