Results 21 to 30 of about 33,363,096 (232)

Apelin-13 enhances arcuate POMC neuron activity via inhibiting M-current. [PDF]

open access: yesPLoS One, 2015
The hypothalamus is a key element of the neural circuits that control energy homeostasis. Specific neuronal populations within the hypothalamus are sensitive to a variety of homeostatic indicators such as circulating nutrient levels and hormones that ...
Lee DK, Jeong JH, Oh S, Jo YH.
europepmc   +2 more sources

Effect of chromosome substitution on intrinsic exercise capacity in mice [v2; ref status: indexed, http://f1000r.es/3jr]

open access: yesF1000Research, 2014
Previous research identified a locus on Chromosome 14 as an important regulator of endurance exercise capacity in mice. The aim of this study was to investigate the effect of chromosome substitution on intrinsic exercise capacity and identify ...
Sean M. Courtney, Michael P. Massett
doaj   +1 more source

KCNQ Current Contributes to Inspiratory Burst Termination in the Pre-Bötzinger Complex of Neonatal Rats in vitro

open access: yesFrontiers in Physiology, 2021
The pre-Bötzinger complex (preBötC) of the ventral medulla generates the mammalian inspiratory breathing rhythm. When isolated in explants and deprived of synaptic inhibition, the preBötC continues to generate inspiratory-related rhythm.
Ann L. Revill   +10 more
doaj   +1 more source

Effect of chromosome substitution on intrinsic exercise capacity in mice [v1; ref status: indexed, http://f1000r.es/2kn]

open access: yesF1000Research, 2014
Previous research identified a locus on Chromosome 14 as an important regulator of endurance exercise capacity in mice. The aim of this study was to investigate the effect of chromosome substitution on intrinsic exercise capacity and identify ...
Sean M. Courtney, Michael P. Massett
doaj   +1 more source

Effect of Iron Oxide Nanoparticles and Amoxicillin on Bacterial Growth in the Presence of Dissolved Organic Carbon

open access: yesBiomedicines, 2017
The impact of emerging contaminants in the presence of active pharmaceutical pollutants plays an important role in the persistence and activity of environmental bacteria.
Kelley M. Current   +2 more
doaj   +1 more source

The Role of Kv7.2 in Neurodevelopment: Insights and Gaps in Our Understanding

open access: yesFrontiers in Physiology, 2020
Kv7.2 subunits encoded by the KCNQ2 gene constitute a critical molecular component of the M-current, a subthreshold voltage-gated potassium current controlling neuronal excitability by dampening repetitive action potential firing.
Nina Dirkx   +5 more
doaj   +1 more source

Data on mass spectrometry-based proteomics for studying the involvement of CYLD in the ubiquitination events downstream of EGFR activation

open access: yesData in Brief, 2018
The present data article corresponds to the proteomic data of the involvement of Cylindromatosis protein (CYLD) in the ubiquitination signaling initiated by EGF stimulation.
Virginia Sanchez-Quiles   +4 more
doaj   +1 more source

Site and Mechanism of ML252 Inhibition of Kv7 Voltage-Gated Potassium Channels

open access: yesFunction, 2023
Kv7 (KCNQ) voltage-gated potassium channels are critical regulators of neuronal excitability and are candidate targets for development of antiseizure medications.
Richard Kanyo   +6 more
doaj   +1 more source

Sterol carrier protein-2 expression alters phospholipid content and fatty acyl composition in L-cell fibroblasts

open access: yesJournal of Lipid Research, 2000
The effects sterol carrier protein-2 (SCP-2) expression on L-cell phospholipid levels and fatty acyl composition was assessed using L-cells transfected with the murine cDNA encoding for either the 15 kDa proSCP-2 or 13.2 kDa SCP-2.
Eric J. Murphy   +2 more
doaj   +1 more source

The current debate: (C+M) E and ultimate harm [PDF]

open access: yesFilozofija i Društvo, 2012
Persson and Savulescu (2011b) is a largely successful defense of the position promoted in Persson and Savulescu (2008) against Fenton’s critique of this position in Fenton (2009).
Rakić Vojin
doaj   +1 more source

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