Results 161 to 170 of about 4,770,227 (300)

Caregiver and Patient Input for Quality and Safety (C-PIQS) Pilot Study: Patient-Initiated Safety Observations Using an m-Health Tool. [PDF]

J Patient Saf
Sharma AE, Avina L, Tran A, Boscardin J, Sosa MC, Garcia M, Solis S, Sarkar U, Rosenbluth G, Stafford M, Harrison JD, Auerbach A, Bardach NS.   +12 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Five years of app evaluation: Insights from a framework in practice - a systematic review on the m-health index and navigation database. [PDF]

Internet Interv
Herpertz J, Dwyer B, Wagner E, Mikkelson J, Opel N, Torous J.   +5 more
europepmc   +1 more source

Evaluation of Usability and User Experience of Oncodoc 's M-Health Application for Early Detection of Cancer. [PDF]

Asian Pac J Cancer Prev, 2022
Wulandari R, Pangarsa EA, Andono PN, Rachmani E, Sidiq M, Setyowati M, Waluyo DE.   +6 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

E-Health and M-Health in Obesity Management: A Systematic Review and Meta-Analysis of RCTs. [PDF]

Nutrients
Chiavarini M, Giacchetta I, Rosignoli P, Fabiani R.   +3 more
europepmc   +1 more source

Mobile Health (m-Health) in Retrospect: The Known Unknowns. [PDF]

Int J Environ Res Public Health, 2022
Istepanian RSH.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Patients' experiences and usability of a self-directed m-health exercise intervention for knee osteoarthritis: a qualitative study. [PDF]

BMJ Open
Dieter V, Schmidt J, Krauss I.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source