An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
LinguAPP: An m-Health Application for Teledentistry Diagnostics. [PDF]
Int J Environ Res Public Health, 2022 Fazio M +8 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Qualitative research for health programmes / Patricia M. Hudelson
, 1994 102 p.The purpose of this guide is to provide an overview of the concepts, methods and tools used in qualitative research and to illustrate how these approaches can support the development, implementation and evaluation of health programmes.
Hudelson, Patricia M +1 more
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Patients' experiences and usability of a self-directed m-health exercise intervention for knee osteoarthritis: a qualitative study. [PDF]
BMJ OpenDieter V, Schmidt J, Krauss I.
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Module 1: general health risks and considerations for travellers
[viii], 7 p.nternational travel involves a range of general health risks influenced by individual characteristics, travel conditions and destination-specific factors, requiring careful preparation and informed decision-making.
World Health Organization
core
Celebrating 10 years of the Irish Health Research Forum 2014-2024 [PDF]
This is a brief overview of the success of the Irish Health Research Forum over 10 years since its foundation in ...
Health Research Charities Ireland
core
A pilot effectiveness study of a just-in-time micro-randomized controlled trial on the physical activity and sedentary time of young children and their parents: The active family m-health intervention. [PDF]
PLoS OnePhillips SM +4 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source