Results 151 to 160 of about 20,132,521 (307)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Reference Values of M-mode Echocardiographic Parameter in Adult Toy Breed Dogs. [PDF]

Front Vet Sci, 2022
Isayama N, Uchimura Y, Sasaki K, Maeda E, Takahashi T, Watanabe M.   +5 more
europepmc   +1 more source

Visite guidée de l'exposition "Déboutonnez la mode", Musée des Arts décoratifs

, 2015
Le séminaire de la mode de l'IHTP propose une visite guidée de l'exposition Déboutonnez la mode au Musée des Arts décoratifs, avec les explications du propriétaire de la collection de boutons exposée, M. Loïc Allio.
Sophie Kurkdjian
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Two-dimensional and M-mode echocardiographic parameters in Ghezel sheep. [PDF]

Vet Res Forum, 2021
Roustaei A, Hashemi-Asl SM, Dalir-Naghadeh B, Masoudifard M.   +3 more
europepmc   +1 more source

9ème séance du séminaire sur la mode de l'IHTP, "Actualité de la recherche en histoire de mode", 20 juin 2014, 14h30

, 2014
La séance du 20 juin 2014 est consacrée, comme l'année dernière, à l'actualité de la recherche en histoire de mode et à la présentation des travaux d' étudiants, de chercheurs et d'auteurs.
Sophie Kurkdjian
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Femoral artery M-mode visualisation of compression dynamics and ROSC transition during CPR. [PDF]

Resusc Plus
Imran MN, Amrithanand VT.
europepmc   +1 more source

Mechanical QT and JT intervals by M-mode echocardiography: An extrapolation from the concurrent electrocardiographic tracings. [PDF]

Ann Pediatr Cardiol, 2022
Rad EM, Ilali HM, Majnoon MT, Zeinaloo A.   +3 more
europepmc   +1 more source