Results 111 to 120 of about 964,507 (280)

M-theory, black holes and cosmology. [PDF]

open access: yesProc Math Phys Eng Sci, 2021
Kallosh R.
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Impact of Majorana fermions on the Kondo state in the carbon nanotube quantum dot

open access: yesJournal of Physics Communications
We have studied the quantum conductance of the Kondo state in the carbon nanotube quantum dot (CNTQD) with side-attached multi-Majorana fermion states in topological superconductors (TSCs).
D Krychowski
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

M-Theory and Cosmology

open access: yes, 2007
JHEP LaTeX, 86 pages, 3 eps ...
openaire   +2 more sources

Minisuperspace models in M-theory [PDF]

open access: yesClassical and Quantum Gravity, 2007
We derive the full canonical formulation of the bosonic sector of 11-dimensional supergravity, and explicitly present the constraint algebra. We then compactify M-theory on a warped product of homogeneous spaces of constant curvature, and construct a minisuperspace of scale factors.
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Hydrodynamics of M-Theory

open access: yes, 2002
We consider the low energy limit of a stack of N M-branes at finite temperature. In this limit, the M-branes are well described, via the AdS/CFT correspondence, in terms of classical solutions to the eleven dimensional supergravity equations of motion ...
Christopher P Herzog   +10 more
core   +4 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

M theory and automorphic scattering [PDF]

open access: yesPhysical Review D, 2001
12 pages, LaTeX; v2 refs added, typos corr; v3 added comments for ref ...
openaire   +2 more sources

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