Results 161 to 170 of about 39,426 (199)

MLKL is involved in the regulation of skin wound healing and interplay between macrophages and myofibroblasts in mice. [PDF]

Sci Rep
Zhao J, Zhang S, Bai Y, Gong Z, Bao W, Yu Z, Liu B, Mao W, Hasi S.   +8 more
europepmc   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro‐Inflammatory Phenotype of Senescent Cells

Aging Cell, EarlyView.
As a natural senomorphic agent, PQQ targets the intracellular molecule. HSPA8 of senescent cells, resulting in significantly reduced expression of the SASP. PQQ holds prominent potential to delay chronological aging and ameliorate age‐related conditions by acting as an effective senomorphic agent.
Birong Jiang, Hongwei Zhang, Qixia Xu, Zhirui Jiang, Ruikun He, Qiang Fu, Yu Sun   +6 more
wiley   +1 more source

Nanoscale Structural Insights into Thermochromic VO₂ Thin Films Using Tip-Enhanced Raman Spectroscopy. [PDF]

ACS Appl Mater Interfaces
Rai A, Bienz S, Hansen VF, Zenobi R, Kumar N.   +4 more
europepmc   +1 more source

Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1

Allergy, EarlyView.
Sequential switching through IgG1 is not required to produce IgE with sufficient allergen‐binding affinity to cause anaphylaxis against food allergens. Sequential switching through IgG1 does not confer a competitive advantage to become an IgE‐expressing cell.
Joshua F. E. Koenig, Adam K. Wade‐Vallance, Rodrigo Jiménez‐Saiz, Kelly Bruton, Siyon Gadkar, Emily Grydziuszko, Tina D. Walker, Melissa E. Gordon, Amy E. Gillgrass, Justin J. Taylor, Susan Waserman, Manel Jordana   +11 more
wiley   +1 more source

Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages. [PDF]

Molecules
Ma Y, Qian X, Yu Q, Dong Y, Wang J, Liu H, Xiao H.   +6 more
europepmc   +1 more source

How and when employees' attributions of their employers' CSR activities affect their extra‐role work behavior

Business Ethics, the Environment &Responsibility, EarlyView.
Abstract The objective of this research is to examine how and when employees' attributions of corporate social responsibility (CSR) affect their extra‐role service behaviors. The research analyses the mediating role of work meaningfulness in the employees' CSR attributions–extra‐role behaviors relationships.
Carmen Castro‐Casal, Guadalupe Vila‐Vázquez, Romina García‐Chas   +2 more
wiley   +1 more source

ZIP10 as a potential therapeutic target in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Increased intracellular zinc levels in acute myeloid leukaemia blasts with upregulated expression of zinc influx transporters ZIP6 and ZIP10. Targeting ZIP10 with a surface antibody represents a potential therapeutic strategy. Created in BioRender. Rolles, B. (2025) https://BioRender.com/bwrtof1.
Benjamin Rolles, Nicolas Chatain, Richard Görg, Margherita Vieri, Nora Tillmann‐Tröster, Marcel G. Bourgeois, Deborah Christen, Jeanette Walter, Addison C. Hillerbrand, Kyle A. Romine, Kathryn M. Taylor, Jens Bertram, Edgar Jost, Steffen Koschmieder, Fabian Beier, Maximilian Stahl, Tim H. Brümmendorf, Lothar Rink, Inga Wessels   +18 more
wiley   +1 more source

Synergistic effects of HO-1 inhibition and chemotherapy on tumor proliferation and immune infiltration: An in vitro and in vivo approach to enhancing prostate cancer treatment. [PDF]

Transl Oncol
Salloom RJ, Sahtout DZ, Ahmad IM, Abdalla MY.   +3 more
europepmc   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

British Journal of Pharmacology, EarlyView.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran, Kevin Winardi, Scott P. Levick, Alexander Widiapradja, Gizem Gemikonakli, Susan E. Howlett, Matthew J. McKay, Mark P. Molloy, John Mach, Sarah N. Hilmer   +9 more
wiley   +1 more source

Identification of Grb2 protein as a potential mediator of macrophage activation in acute pancreatitis based on bioinformatics and experimental verification. [PDF]

Front Immunol
Shen Q, Wang S, Wu K, Wang L, Gong W, Lu G, Chen W, Yuan C, Tu B, Li W, Wang Y, Yang W.   +11 more
europepmc   +1 more source