Results 181 to 190 of about 39,426 (199)

Cardioprotective effects of the extracellular chaperone clusterin in acute myocardial infarction

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
In vivo, CLU−/− mice were more susceptible to acute myocardial infarction than CLU+/+ mice. Moreover, inflammation and histone levels were significantly increased in CLU−/− mice compared to CLU+/+ mice following ischemia/reperfusion. In vitro, CLU protects cardiomyocytes from histone‐ and/or hypoxia‐induced cell death.
Louwana Allawa   +12 more
wiley   +1 more source

Gender beliefs and legitimization of dating violence in adolescents. [PDF]

open access: yesOpen Med (Wars)
Ferreira SB   +3 more
europepmc   +1 more source

Distinct impacts of sodium channel blockers on the strength–duration properties of human motor cortex neurons

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to determine how voltage‐gated sodium channel (VGSC) blockers modulate cortical excitability in vivo. VGSCs are critical for regulating axonal excitability, yet the effects of sodium channel‐blocking medications on human cortical neurons remain poorly characterized.
Lorenzo Rocchi   +6 more
wiley   +1 more source

Regional specialization of movement encoding across the primate sensorimotor cortex. [PDF]

open access: yesNat Commun
Borgognon S   +15 more
europepmc   +1 more source

Membrane selectivity and pore formation of SprA1 and SprA2 hemolytic peptides from Staphylococcus aureus type I toxin–antitoxin systems

open access: yesThe FEBS Journal, EarlyView.
When overexpressed in Staphylococcus aureus, the type I toxins SprA1 and SprA2 form membrane pores, with SprA1 creating stable pores and SprA2 forming transient ones. Both induce concomitant membrane depolarization, ATP release, and growth arrest, while only SprA1 causes membrane permeabilization due to its stable pore formation.
Laurence Fermon   +10 more
wiley   +1 more source

Identifying cognitive‐affective mechanisms underlying disability in episodic migraine: Using the fear avoidance model to examine interactions

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective Using the fear‐avoidance model (FAM) as a theoretical framework, this study examined the interactions between empirical factors contributing to disability in episodic migraine. It was tested whether pain catastrophizing, fear of attacks, and depressiveness mediate the relationship between pain experience and disability.
Janosch Fox   +6 more
wiley   +1 more source

Overestimation of Automated Platelet Counts by Blast Fragments in Acute Hypercellular Leukemias: A Retrospective Study Comparing Impedance, Optical (PLT‐O), Fluorescent (PLT‐F), and CD41/CD61 Flow Cytometry Methods

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Acute leukemias with hyperleukocytosis (> 100 × 109/L) can produce cytoplasmic blast fragments that interfere with platelet counts, notably in impedance‐based methods, potentially masking severe thrombocytopenia and increasing hemorrhagic risk.
Victor Bobée   +10 more
wiley   +1 more source

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