Results 191 to 200 of about 284,413 (281)

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections. [PDF]

Clin Sci (Lond)
Liu Z, Ren P, Xue Y, Liu S, Li S, Li Y, Zhang Y.   +6 more
europepmc   +1 more source

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

Allergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu   +14 more
wiley   +1 more source

The intrinsic time tracker: temporal context is embedded in entorhinal and hippocampal functional connectivity patterns. [PDF]

Nat Commun
Wang J, Tambini A, Pritschet L, Taylor CM, Jacobs EG, Lapate RC.   +5 more
europepmc   +1 more source

Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters

Andrology, EarlyView.
ABSTRACT Background Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on the effects of EVs on spermatozoa have focused on ejaculated spermatozoa, which have already been exposed to their own native
Ana Moya‐Fernández, Santa María Toledo‐Guardiola, Peter Silke, Sergio Navarro‐Serna, Carmen Matás   +4 more
wiley   +1 more source

Tailored GAFF Parameters for Pentamethylcyclopentadienyl Rh(I/III) Complexes with α-Diimine Ligands: Validation and Solvation Studies. [PDF]

J Phys Chem B
Jacobi R, Zois KP, Mengele AK, Rau S, González L.   +4 more
europepmc   +1 more source

Effects of body size on suspension feeding and energy budgets of the pearl oysters Pinctada margaritifera and P. maxima

, 1998
H. Yukihira, D. Klumpp, J. Lucas
semanticscholar   +1 more source

Can Technological and Customer Competencies Enable the Firm to Be Greener? Simultaneous Consideration of Resource‐Based View and Social License to Operate

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT This research explores the contribution of firm competencies and green management practices to enhancing a firm's sustainable performance. It examines the effects of technological competencies (TC) and customer competencies (CC) through the lens of a competence‐based view (CBV) framework, particularly focusing on their influence on green ...
Tongkyu Kim, Hyeonyu Son, Yu Ri Kim, Jiyeon Han, Yunze Cho, Taewoo Roh   +5 more
wiley   +1 more source

Ethyl Acetate Extract of <i>Cynanchi Auriculati Radix</i> Inhibits LPS-Induced M1 Polarization of RAW264.7 Macrophages and Prolongs the Lifespan of <i>Caenorhabditis elegans</i> by Regulating NF-κB and PMK-1/SKN-1 Signaling Pathways. [PDF]

Curr Issues Mol Biol
Fan J, Su Y, Xing Y, Hu K, Ren J, Yang J.   +5 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source