Results 21 to 30 of about 25,707 (149)
Enhanced Oxygen Evolution Kinetics via Single‐Atom Catalyst Design: A Review
Advanced Materials Interfaces, EarlyView.Single atom catalysts (SACs) in oxygen evolution reaction (OER). TOC shows key aspects like synthetic strategies, supports‐selection principle, metal types, and OER performances in SACs. Abstract This review highlights recent advancements in enhancing oxygen evolution reaction kinetics through the design of single‐atom catalysts.
Zhen Yuan +7 more
wiley +1 more source
Mie‐Resonant Metasurfaces with Controlled Silicon Oxidation in Electron‐Beam Deposition
Advanced Materials Interfaces, EarlyView.Electron‐beam deposition is optimized to prevent silicon oxidation by controlling chamber pressure and deposition rate, yielding refractive index values comparable to other methods. This tunability enables precise control of optical properties. Mie‐resonant metasurfaces exhibit strong, tunable collective resonances, allowing the fabrication of silicon ...
Neal Raney, Viktoriia E. Babicheva
wiley +1 more source
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.This study presents a microfluidic wet spinning technique for producing ultrathin, templated collagen sheets with hierarchical organization at the microscale. The aligned collagen sheets replicate strain‐stiffening behavior associated with native cardiovascular tissues, sup cell attachment and contraction, and enable biofabrication of load‐bearing ...
Yuming Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng +11 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals histone lactylation as a metabolic‐epigenetic regulator countering cellular senescence and skeletal muscle aging. Reduced lactylation impairs cell cycle, DNA repair and proteostasis pathways, while exercise restores glycolytic activity and lactylation levels, preserving muscle function.
Fanju Meng +16 more
wiley +1 more source
Advanced Science, EarlyView.Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang +11 more
wiley +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
Advanced Science, EarlyView.This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan +12 more
wiley +1 more source
Advanced Science, EarlyView.Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang +7 more
wiley +1 more source
Advanced Science, EarlyView.The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang +12 more
wiley +1 more source