Results 31 to 40 of about 45,204 (255)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

O traktorze pędzącym w rytm Kalinki. Folklor w filmach animowanych Europy Środkowo- -Wschodniej powstałych w latach 1949–1984

open access: yesEdukacja Muzyczna, 2019
Filmy animowane dla dzieci zasługują na uwagę nie tylko jako utwory ukierunkowane na prze- kazywanie treści dydaktycznych, czy też mające zapewnić najmłodszym widzom rozrywkę – nieraz dokumentują rzeczywistość, utrwalają ...
Katarzyna BABULEWICZ
doaj   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

open access: yesAdvanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Wątki polskie w mszach Jana A. Maklakiewicza i Tadeusza Maklakiewicza

open access: yesEdukacja Muzyczna, 2019
Przedmiotem artykułu są dwie msze z tekstem polskim, które – według typologii Stanisława Dąbka – reprezentują typ tzw. mszy polskiej, znamiennej dla twórczości polskich kompozytorów pierwszej połowy XX wieku.
Monika KARWASZEWSKA
doaj   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad   +7 more
wiley   +1 more source

Asymilacja ludowych pierwowzorów w polskiej pieśni artystycznej – zarys problematyki

open access: yesEdukacja Muzyczna, 2019
Głównym celem artykułu jest przedstawienie różnych sposobów funkcjonowania pieśni ludo-wych (głównie pieśni słowiańszczyzny) w polskiej pieśni artystycznej od momentu jej powstania(uznając za ojców pieśni polskiej S. Moniuszkę i F.
Katarzyna SUSKA-ZAGÓRSKA
doaj   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Noise as a Spectre in Dub Techno

open access: yesDancecult: Journal of Electronic Dance Music Culture
This article explores dub techno's history and sonic characteristics, focusing on the role of noise as a critical stylistic element. It introduces hauntology as a hermeneutic framework to understand the intricate function of noise within the genre. This
Bahadırhan Koçer
doaj   +1 more source

First Results from MFOSC-P : Low Resolution Optical Spectroscopy of a Sample of M dwarfs within 100 parsecs

open access: yes, 2020
Mt. Abu Faint Object Spectrograph and Camera (MFOSC-P) is an in-house developed instrument for Physical Research Laboratory (PRL) 1.2m telescope at Mt. Abu India, commissioned in February 2019.
Allard, F.   +6 more
core   +3 more sources

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