Results 51 to 60 of about 220,787 (262)

Nano‐Enabled Systemic Delivery of STING Agonist by Engineered Silicasome for Potent Antitumor Immunotherapy

Advanced Science, EarlyView.
Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou, Yuting Li, Xudong Sun, Honghong Yang, Xiayu Shi, Lijia Yao, Jinhong Jiang, Erli Wang, Haoyang Wang, Yi Wei, Xiangsheng Liu   +10 more
wiley   +1 more source

Theoretical calculation of internal conversion coefficients for multipole transitions in 88Sr nucleus

Iraqi Journal of Physics, 2012
Internal conversion coefficients (ICC) and electron–positron pair conversion coefficients (PCC) for multipole transition of the core nucleus 88Sr have been calculated theoretically.
Ali A. Alzubadi
doaj  

Pedagogical Approaches to Mastering Polyphonic Cycles by J. S. Bach and D. D. Shostakovich in the Piano Class by Students of the People’s Republic of China [PDF]

Музыкальное искусство и образование, 2019
In the article the problems of mastering the binary cycles by J. S. Bach and D. D. Shostakovich included in large-scale polyphonic collections of the composers (“Well-Tempered Clavier” and “Twenty-Four Preludes and Fugues”, opus 87) by the Chinese piano ...
Elena P. Krasovskaya, Ho Da
doaj   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

Advanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun, Miji Kim, Wooyeon Shin, Yongjun Park, Kanghwan Kim, Il‐Joo Cho, Jae Won Shim, Min Soo Kim, Sunwoo Lee, Jeongjin Kim, Changhyuk Lee   +10 more
wiley   +1 more source

GMT M1 subsystem: status, design and testing

, 2018
This paper describes the design, status, and test program for the Giant Magellan Telescope (GMT) Primary Mirror Subsystem (M1). It consists of the mirror cells, positioning system, support systems, and thermal control system.
Aguayo, Francisco, Abhijit Wadhavkar, Trupti Ranka, Kechichian, Zaven, Peter Gray, Ranka, Trupti, Ford, John, Gusick, Michael, Barbara Fischer, Erich Bugueno, Francisco Aguayo, David S. Ashby, Hector Swett, Gray, Peter, Dev Sharma, Jose Soto, Anthony Hebert, Ashby, David S., Divya Thanasekaran, Bugueno, Erich, Tian, Frank, Fischer, Barbara, Swett, Hector, Soto, Jose, Michael Gusick, Hebert, Anthony, Wadhavkar, Abhijit, Thanasekaran, Divya, Zaven Kechichian, John Ford, Sharma, Dev, Frank Tian   +31 more
core   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

What is a "Lament," Really?: A Commentary on Nicholas Shea's "Descending Bass Schemata and Negative Emotion in Western Song"

Empirical Musicology Review, 2020
This commentary focuses on Shea (2019) and its relationship to much of the literature on popular and rock music. The commentary offers some methodological considerations on the construction of corpora for this type of analysis.
Bryn Hughes
doaj   +1 more source

Physical oceanography at time series station S2-M1-CTD1

, 2015
Physical oceanography at time series station S2-M1 ...
Anna Lichtschlag (6962609), Janssen, Felix, Holtappels, Moritz, Lichtschlag, Anna, Jan Fischer (720642), Fischer, Jan, Felix Janssen (7882721), Moritz Holtappels (6959561)   +7 more
core   +1 more source