Results 61 to 70 of about 45,204 (255)

Ирригационная терапия в комплексном лечении воспалительных заболеваний верхних дыхательных путей (ВДП) и уха [PDF]

open access: yes, 2021
ДЫХАТЕЛЬНЫЕ ПУТИУХОИРРИГАЦИЯИРРИГАЦИОННАЯ ТЕПАРИЯВОСПАЛИТЕЛЬНЫЕ ЗАБОЛЕВАНИЯВЕРХНИЕ ДЫХАТЕЛЬНЫЕ ...
Трущенко, О. В.
core  

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu   +13 more
wiley   +1 more source

Měnín and Telnice - bypass study [PDF]

open access: yes, 2018
Předmětem této bakalářské práce je vyhledávací studie obchvatu obcí Telnice a Měnín. Tyto obce se nachází v okrese Brno - venkov, Jihomoravský kraj. Obchvat Telnice bude navržen jako komunikace kategorie S9,5/80 a bude se napojovat na stávající silnici ...
Šnédar, Jaroslav
core   +1 more source

Numerical models of planetary nebulae with different episodes of mass ejection: the particular case of HuBi 1

open access: yes, 2023
We have studied the evolution of HuBi 1-like planetary nebulae, considering several stages of mass injection. We have carried out numerical ionization+1D hydrodynamics+atomic/ionic rate models with our code Coral 1D to reproduce planetary nebulae that ...
Castorena, Jorge Ivan   +6 more
core  

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu   +15 more
wiley   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy

open access: yesAdvanced Science, EarlyView.
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen   +14 more
wiley   +1 more source

Urban study of development area Vítkovice - Moravská Ostrava [PDF]

open access: yes, 2016
Diplomová práce se zabývá rozvojem oblasti v blízkosti centra města Ostravy. Řešené území se nachází na jížní hranici městské části Moravská Ostrava a Přívoz a je defiována ulicemi k Trojhalí, Místecká, železničními tratěmi 321 a 323 a řekou Ostravicí ...
Vrtek, Tomáš
core  

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao   +3 more
wiley   +1 more source

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