Results 1 to 10 of about 7,096 (148)

Directed Evolution of T7 RNA Polymerase Minimizes dsRNA By-product and Enables High-Fidelity mRNA Synthesis for Demanding Therapeutic Applications [PDF]

Research
T7 RNA polymerase (T7 RNAP) is the most widely used enzyme for synthesizing therapeutic mRNA. However, RNA transcribed by T7 RNAP often contains double-stranded RNA (dsRNA) by-products that trigger innate immune responses and complicate purification ...
Weitong Qin, Ting Nie, Mohan Hei, Liang Li, Yunjie Pan, Manjie Luo, Guang-Yu Yang   +6 more
doaj   +2 more sources

Corrosion resistance studies on the concrete made with basalt fibres and basalt fibre reinforced rebars [PDF]

E3S Web of Conferences, 2021
In the present work, assessment of corrosion resistance for M30 grade concrete made with basalt fibres in terms of Resistivity, Potentials and Chloride ion diffusion is made to understand the corrosion resistance studies of concrete specimen made with ...
Goud E Giri Prasad, Kannimuthu Marimuthu, Reddy V Srinivasa, Saikrishna V   +3 more
doaj   +1 more source

Food safety knowledge and practices among fresh coconut vendors

Scientific African, 2020
The study examines the distribution and sale practices of coconut vendors, identifies and analyzes food safety bottlenecks associated with street vending of fresh coconuts in Accra, Ghana.
C. Oduro-Yeboah, N.B. Ackah, P.T. Akonor, S.K. Amponsah, F.P. Mboom   +4 more
doaj   +1 more source

Prognostic biomarkers in lung cancer patients in terms of long-term survival

Turkish Journal of Internal Medicine, 2021
Introduction: We aimed to investigate the predictive effect of serum M30 and M65 antigens on long-term prognosis in patients with advanced stage lung cancer before and after the first dose of chemotherapy.
Belkis Nihan Coskun, Engin Ulukaya, Türkkan Evrensel, Şeniz Korkmaz, Oğuzhan Sıtkı Dizdar   +4 more
doaj   +1 more source

Motivations of guests contributing sWOM on social media: a case in Vietnam [PDF]

Journal of Asian Business and Economic Studies, 2022
Purpose – This paper examines whether guests contribute sWOM (social word of mouth) on different SNSs (social networking sites) regarding various personal motivations. SNSs have changed the way guests eat and experience their food and dishes.
Le Thi Thanh Ha, Vo Thanh Thu
doaj   +1 more source

The Dynamic Influence of Olorofim (F901318) on the Cell Morphology and Organization of Living Cells of Aspergillus fumigatus

Journal of Fungi, 2020
The first characterized antifungal in the orotomide class is olorofim. It targets the de novo pyrimidine biosynthesis pathway by inhibiting dihydroorotate dehydrogenase (DHODH).
Saskia du Pré, Mike Birch, Derek Law, Nicola Beckmann, Graham E. M. Sibley, Michael J. Bromley, Nick D. Read, Jason D. Oliver   +7 more
doaj   +1 more source

Serum keratin‐18 detects hepatic inflammation and predicts progression in compensated alcohol‐associated liver disease

Hepatology Communications, 2022
Alcohol‐associated liver fibrosis accumulates over decades, driven by hepatic inflammation and cell death. We investigated the diagnostic accuracy of keratin‐18 degradation, measured using serum M30 and M65 levels, and the ActiTest for hepatic ...
Katrine Holtz Thorhauge, Maja Thiele, Sönke Detlefsen, Ditlev Nytoft Rasmussen, Stine Johansen, Bjørn Stæhr Madsen, Steen Antonsen, Lars Melholt Rasmussen, Katrine Prier Lindvig, Aleksander Krag   +9 more
doaj   +1 more source

Chemical, Microbial Quality, and Risk Assessment due to Toxic Metal Contamination of Egusi (Citrullus colocynthis L.) Powder Sold in Selected Ghanaian Markets

International Journal of Food Science, 2020
The present study was undertaken to investigate the physicochemical and microbiological qualities of melon seed powder sold in some open Ghanaian markets.
Winifred Arthur, Jemima Ofori, Peter Addo, Nelson Amey, Nii Korley Kortei, Paa Toah Akonor   +5 more
doaj   +1 more source

Efeitos observados com diferentes doses de morfina subaracnóidea em ratos Efectos observados con diferentes dosis de morfina subaracnoidea en ratones Effects of different spinal morphine doses in rats

Revista Brasileira de Anestesiologia, 2004
JUSTIFICATIVA E OBJETIVOS: A morfina por via espinhal promove bom efeito analgésico, mas não é isenta de efeito colateral. O objetivo deste estudo foi investigar os efeitos observados com diferentes doses de morfina por via subaracnóidea.
Neuzimar de Souza Freire Silva, Rioko Kimiko Sakata, Adriana Machado Issy   +2 more
doaj   +1 more source

Combined Serum Biomarkers in Non-Invasive Diagnosis of Non-Alcoholic Steatohepatitis. [PDF]

PLoS ONE, 2015
Non-alcoholic steatoheaptitis (NASH), the critical stage of non-alcoholic fatty liver disease (NAFLD), is of chronic progression and can develop cirrhosis even hepatocellular carcinoma (HCC).
Mei Yang, Dongping Xu, Yuan Liu, Xiaodong Guo, Wenshu Li, Chaonan Guo, Hongping Zhang, Yinjie Gao, Yuanli Mao, Jingmin Zhao   +9 more
doaj   +1 more source