Results 71 to 80 of about 85,903 (285)

Sacred Spaces in a World of Movement

Religions
In the social sciences, the mobilities paradigm studies people in movement in contrast to a sedentary paradigm that treats dwelling as being at peace and at home.
Tianyin Xia
doaj   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

DataSheet1_Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation.PDF

, 2021
Ionotropic glutamate receptors (iGluRs) are tetrameric ligand-gated ion channels that play a crucial role in excitatory synaptic transmission in the central nervous system.
Kai Langer (11509666), Bodo Laube (1881139), Adriana Müller-Längle (11509669), Jannik Wempe (11509672)   +3 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Politiques linguistiques et interprétation en milieu social au Canada : des droits linguistiques aux droits d’accès aux services publics [PDF]

Çédille: Revista de Estudios Franceses, 2014
This contribution explores the importance of the interpreter as a vector of distinction between linguistic rights and rights of access to public services in the Canadian context.
Juan Jiménez-Salcedo
doaj  

On interaction in extended particle model on (M4 x M4) x Z4

, 2001
15 pages, LaTeX; Subsections and e-mail Added, typos ...
Smida, A., Hachemane, M., Hamici, A. H., Djelid, R.   +3 more
openaire   +2 more sources

Mga is required for the M4-LC-1 surface phenotype.

, 2018
(A) Relative abundance of cell-surface proteins in isogenic M4-SC-1ΔcovS mutant compared to the wild type CovS intact M4-SC-1 strain as determined by MassSpec analysis of shaved surface proteins.
Awdhesh Kalia (78115), Micah M. Bhatti (6054020), Truc T. Tran (310042), Samuel A. Shelburne (251582), Ken Chen (61463), Xiqi Li (6054014), Cesar A. Arias (310046), Anthony R. Flores (405428), Erika J. Thompson (6054017), Sruti DebRoy (159313), Vance G. Fowler Jr. (223373), David H. Hawke (460602), Jessica Galloway-Peña (186182), Bih-Fang Pan (4255138), Nicola Horstmann (201711), Fang Wang (105926), Hui Yao (240607), Chelcy Brumlow (5917472)   +17 more
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Interculturalité, multiculturalité et transculturalité dans la Traduction et l'Interprétation en Milieu Social [PDF]

Çédille: Revista de Estudios Franceses, 2014
The «chameleonic» notions of interculturality, multiculturality and transculturality have been widely used in the last years within Translation Studies as a description of translations and interpreting practices that were apparently aimed at resolving ...
José Yuste Frías
doaj  

M4 receptor immunohistochemistry.

, 2019
(A) Representative images of M4 receptor (green) in striatum and motor cortex of DYT1 KI (DYT1) and wildtype (WT) mice, scale bar is 20 μm; negative control without primary antibody and corpus callosum show no specific staining as expected ...
Laura Klein (8087729), Angelika Richter (8087732), Christin Helmschrodt (780525), Franziska Richter (7826633)   +3 more
core   +1 more source