Results 1 to 10 of about 23,917 (146)

Distinct characteristics of VEXAS-causative UBA1 M41 and recurrent functional non-M41 mutations. [PDF]

Leukemia
Abstract VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a severe inflammatory and hematologic disease caused by somatic mutations in UBA1 . Canonical pathogenic mutations at UBA1 p.Met41 (M41) lead to the ...
Sakuma M, Wang AK, Magaziner SJ, Keane SP, Meggendorfer M, Kern W, Haferlach C, Haferlach T, Beck DB, Walter W.   +9 more
europepmc   +2 more sources

Physicochemical, Functional, Sensory Properties and Willingness to Consume Porridge Made From Composite Flours of Maize, Soybean, and Ripe Plantain. [PDF]

Food Sci Nutr
This study aims to enhance the nutritional quality of maize porridge, a popular meal in many developing countries, by adding soybean and ripe plantain flours which are rich in protein and β‐carotene, respectively. The addition of soybean and ripe plantain to form composite flour did not affect water binding, swelling power, and viscosity compared to ...
Otoo GS, Kizzie-Hayford N, Dadzie RG, Seidu-Larry S, Gyimah CA, Geraldo V, Kaburi SA, Lamptey FP, Adade I, Ampofo-Asiama J.   +9 more
europepmc   +2 more sources

Beliefs and Behaviors Related to Physical Activity in Black Girls With Asthma. [PDF]

Pediatr Pulmonol
ABSTRACT Introduction and Objective Physical activity (PA) is associated with improved asthma outcomes. Black girls face higher rates of asthma morbidity and are less likely to meet recommended PA than their White and Black male peers. To address these health disparities, it is essential to understand beliefs and behaviors related to PA among Black ...
Spadoni N, Cavalier A, Davis E, Salvo D, Langer S, Nyenhuis SM, Volerman A.   +6 more
europepmc   +2 more sources

S161: UBA1 NON-M41 VARIANTS ARE MORE AGGRESSIVE THAN UBA1 M41 VARIANTS IN THEIR HEMATOLOGICAL MANIFESTATIONS. [PDF]

Hemasphere, 2023
Sakuma M, Baer C, Meggendorfer M, Haferlach C, Kern W, Haferlach T, Walter W.   +6 more
europepmc   +3 more sources

UBA1 Non-M41 Variants Are More Aggressive than UBA1 M41 Variants in Their Haematological Manifestations

EMJ Hematology, 2023
BACKGROUND AND AIMS In 2020, three somatic mutations in the X-linked gene UBA1, coding for an essential ubiquitin activating enzyme, were reported to cause VEXAS syndrome, a novel haemato-inflammatory disease that manifests with both cytopenias and autoinflammation.1 The mutations alter the start codon (M41) of the cytoplasmic isoform of UBA1 ...
Sakuma, Maki, Baer, Constance, Meggendorfer, Manja, Haferlach, Claudia, Kern, Wolfgang, Haferlach, Torsten, Walter, Wencke   +6 more
openaire   +1 more source

Evaluating Modelling Approaches for Medical Image Annotations [PDF]

, 2010
Information system designers face many challenges with regards to selecting appropriate semantic technologies and deciding on a modeling approach for their system.
Bijan Parsia, Jasmin Opitz, Ulrike Sattler   +2 more
core   +5 more sources

Monomial, Gorenstein and Bass Orders [PDF]

, 2015
In this article we study a class of orders called {\it monomial orders} in a central simple algebra over a non-Archimedean local field. Monomial orders are easily represented and they may be also viewed as a direct generalization of Eichler orders in ...
Yang, Tse-Chung, Yu, Chia-Fu
core   +1 more source

Prepotentials of N=2 SU(2) Yang-Mills theories coupled with massive matter multiplets [PDF]

, 1996
We discuss N=2 SU(2) Yang-Mills gauge theories coupled with N_f (=2,3) massive hypermultiplets in the weak coupling limit. We determine the exact massive prepotentials and the monodromy matrices around the weak coupling limit.
Ohta, Yuji
core   +2 more sources

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]

, 2013
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund, Badens, Baker, Berk, Berube, Blanchette, Carolin Bürck, Chatterjee, Cheng, Chinnadurai, Cuchet-Lourenco, Dallaire, Dellaire, Dobner, Drane, Everett, Flint, Frisch, Gibbons, Glass, Goldberg, Goldberg, Gostissa, Graham, Groitl, Gunther, Hancock, Harlow, Hassan, Hollenbach, Ishov, Ishov, Jin, Kahyo, Kindsmuller, Kindsmuller, Kindsmüller, Ko, Komatsu, Kosulin, Lewis, Lewis, Li, Lukashchuk, Lukashchuk, Mandy Glass, Marton, Matsumoto, Maul, McFarlane, Michaelson, Mitsudomi, Mund, Nevels, Nevins, Nevins, Niforou, Okuwaki, Orazio, Parks, Pelka, Peter Groitl, Peter Wimmer, Placek, Querido, Roger D. Everett, Ross, Rubenwolf, Sabrina Schreiner, Salomoni, Sarah Kinkley, Sarnow, Schreiner, Schreiner, Schreiner, Shenk, Si, Song, Stracker, Takahashi, Tang, Thomas Dobner, Torii, Täuber, Täuber, Ullman, White, Williams, Wilson, Wong, Wong, Xu, Xue   +92 more
core   +1 more source

Enumeration of graphs with a heavy-tailed degree sequence [PDF]

, 2016
In this paper, we asymptotically enumerate graphs with a given degree sequence d=(d_1,...,d_n) satisfying restrictions designed to permit heavy-tailed sequences in the sparse case (i.e. where the average degree is rather small).
Gao, Pu, Wormald, Nicholas
core   +1 more source