Distinct characteristics of VEXAS-causative UBA1 M41 and recurrent functional non-M41 mutations [PDF]
Abstract VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a severe inflammatory and hematologic disease caused by somatic mutations in UBA1 . Canonical pathogenic mutations at UBA1 p.Met41 (M41) lead to the ...
Maki Sakuma +2 more
exaly +4 more sources
Com o objetivo de avaliar as afinidades antigênicas entre 14 amostras de vírus da bronquite infecciosa das galinhas (VBIG) isoladas de casos clínicos ocorridos entre 1972 e 1989 no Estado de Minas Gerais, sua reatividade frente a dois anticorpos ...
M.B. Souza, N.R.S. Martins, J.S. Resende
doaj +2 more sources
مطالعه ایمنی متقاطع دو واکسن کشته روغنی تهیه شده با سویه M41 و سویه ایرانی IR/773/2001 از سروتیپ 793/B در جوجه های SPF [PDF]
این مطالعه برای تعیین ایمنی متقاطع بین سویه M41 از سروتیپ ماساچوست و سویه ایرانی IR/773/2001 از سروتیپ 793/B ویروس برونشیت عفونی انجام گرفت. دو گروه 20 قطعه ای جوجه SPF در سن سه هفتگی با دو واکسن کشته روغنی تجربی برونشیت عفونی تهیه شده با سویه های M41 و ...
. شوشتری +4 more
doaj +2 more sources
Induction of antiviral RNA interference by avian coronavirus IBV in PBMCs-Mφ [PDF]
Infectious bronchitis virus (IBV), a member of the gammacoronavirus family, can easily mutate, resulting in different subtypes of strains. QX and M41, two subtypes of IBV, exhibit distinct characteristics in terms of their pathogenicity and infection ...
Yaotang Wu +7 more
doaj +2 more sources
N-glycosylation of infectious bronchitis virus M41 spike determines receptor specificity [PDF]
Infection of chicken coronavirus infectious bronchitis virus (IBV) is initiated by binding of the viral heavily N-glycosylated attachment protein spike to the alpha-2,3-linked sialic acid receptor Neu5Ac. Previously, we have shown that N-glycosylation of recombinantly expressed receptor binding domain (RBD) of the spike of IBV-M41 is of critical ...
Bouwman, K.M. +7 more
core +10 more sources
Input Layer Regularization and Automated Regularization Hyperparameter Tuning for Myelin Water Estimation Using Deep Learning. [PDF]
We propose a novel deep learning algorithm for predicting the myelin water fraction from multiple gradient‐echo or spin‐echo pulse sequences arising in magnetic resonance relaxometry (MRR) measurements of the human brain. Our method incorporates both regularized nonlinear least squares and pure deep learning through a concatenation paradigm known as ...
Modi M +7 more
europepmc +2 more sources
Genotype V (GV) Japanese encephalitis virus (JEV) has emerged in Korea and China since 2009. Recent findings suggest that current Japanese encephalitis (JE) vaccines may reduce the ability to induce neutralizing antibodies against GV JEV compared to ...
Shigeru Tajima +6 more
doaj +1 more source
Physicochemical, Functional, Sensory Properties and Willingness to Consume Porridge Made From Composite Flours of Maize, Soybean, and Ripe Plantain. [PDF]
This study aims to enhance the nutritional quality of maize porridge, a popular meal in many developing countries, by adding soybean and ripe plantain flours which are rich in protein and β‐carotene, respectively. The addition of soybean and ripe plantain to form composite flour did not affect water binding, swelling power, and viscosity compared to ...
Otoo GS +9 more
europepmc +2 more sources
Potential probiotic Pediococcus pentosaceus M41 modulates its proteome differentially for tolerances against heat, cold, acid and bile stresses [PDF]
we have evaluated the differential proteomic responses of a potential novel probiotic Pediococcus pentosaceus M41 under heat, cold, acid, and bile stress conditions.
Ayyash, M (via Mendeley Data)
core +2 more sources

