Results 211 to 220 of about 8,203 (227)

Methylated RNA Immunoprecipitation Assay to Study m5C Modification in Arabidopsis.

Journal of visualized experiments : JoVE, 2020
Secondary base modifications on RNA, such as m5C, affect the structure and function of the modified RNA molecules. Methylated RNA Immunoprecipitation and sequencing (MeRIP-seq) is a method that aims to enrich for methylated RNA and ultimately identify modified transcripts.
Saplaoura, Eleftheria, Perrera, Valentina, Colot, Vincent, Kragler, Friedrich   +3 more
openaire   +3 more sources

Changes of RNA m6A/m5C Modification Regulatory Molecules in Ferroptosis of T2DM Rat Pancreas

Cell Biochemistry and Biophysics
N6-methyladenine (m6A) and 5-methylcytosine (m5C) are two common forms of RNA methylation that play an important role in the epigenetics of type 2 diabetes mellitus (T2DM). One type of cell death, ferroptosis, has been implicated in islet β-cell damage in T2DM.
Xiaoyu Liu, Nan Wang, Shiyan Gu, Zuoshun He   +3 more
openaire   +2 more sources

NSUN2-mediated m5C modification of circFAM190B promotes lung cancer progression by inhibiting cellular autophagy

International Journal of Biological Macromolecules
5-Methylcytosine (m5C) modification is an important type of RNA methylation. Diverse noncoding RNAs can undergo m5C modification and play important roles in tumour development, but circRNA m5C modifications have not been fully revealed in tumours. Here, circFAM190B, which was significantly overexpressed in lung cancer cells and tissues, was identified ...
Sixian, Chen, Dunyu, Cai, Qingyun, Zhao, Jiaxi, Wu, Xiaodong, Zhou, Haotian, Xu, Xiaofei, Li, Ruirui, Zhang, Wenyi, Peng, Gang, Li, Aruo, Nan   +10 more
openaire   +2 more sources

NSUN2 Promotes Prostate Cancer Cell Proliferation and Migration Through m5C Modifications of YES1

Molecular Carcinogenesis
ABSTRACT Prostate cancer (PCa) is one of the most common genitourinary malignancies in men worldwide. As a 5‐methylcytosine (m5C) methyltransferase, NSUN2 has been implicated in regulating PCa progression. This study aimed to investigate the role of NSUN2 in PCa and elucidate its underlying mechanisms.
Tianming Chen, Xiaokang Yang, Shuai Su, Delin Wang   +3 more
openaire   +1 more source

The emerging role of m5C modification in viral infection

Virology
Jincheng Li, Leiliang Zhang
openaire   +1 more source

Erratum: Methylated RNA Immunoprecipitation Assay to Study m5C Modification in Arabidopsis.

Journal of visualized experiments : JoVE
An erratum was issued for: Methylated RNA Immunoprecipitation Assay to Study m5C Modification in Arabidopsis. The author list was updated. The author list was updated from: Eleftheria Saplaoura1, Valentina Perrera2, Friedrich Kragler1 1Max Planck Institute of Molecular Plant Physiology 2Department of Molecular Medicine, Medical School, University of ...
openaire   +1 more source

mRNA m5C controls adipogenesis by promoting CDKN1A mRNA export and translation

RNA Biology, 2021
Ruifan Wu, yizhen wang, Xinxia Wang
exaly  

The Lack of Functional DNMT2 Gene Modulates Gvhd Process Via tRNA m5c Modification

Blood, 2022
Huanping Guo, Chao Ma, Rui Wang, Ting Chen, Yun-Jing Zeng, Shijie Yang, Yunfang Zhang, Xi Zhang   +7 more
openaire   +1 more source

Mechanism of puerarin alleviating myocardial remodeling through NSUN2-mediated m5C methylation modification

Phytomedicine
Wu Yahua, Huang Xiaomin, He Yun, Chang Junjie, Fang Xiaoxia, Kang Pengju, Na Feng, Rui Liu, Xiao Pingping, Dandan Shi, Zhang Qiufang, Yan Ding, Wenjun Zhang, Xiju He   +13 more
openaire   +1 more source

5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader

Cell Research, 2017
Ying Yang, Baofa Sun, Yu-Sheng Chen
exaly