Results 201 to 210 of about 8,203 (227)

Metabolic Recoding of NSUN2-Mediated m⁵C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m⁵C-ENO1 Positive Feedback Loop. [PDF]

Adv Sci (Weinh)
Chen B, Deng Y, Hong Y, Fan L, Zhai X, Hu H, Yin S, Chen Q, Xie X, Ren X, Zhao J, Jiang C.   +11 more
europepmc   +1 more source

The Effect of Cytosine Methylation on the Structure and Geometry of the Holliday Junction: The Structure of d(CCGGTACm5 CGG) at 1.5 Å Resolution

, 2002
Ho, P. Shing, Vargason, Jeff
core  

m6A and m5C modifications as the gears: CmoCK1 mRNA travels to promote chilling tolerance

Plant Physiology
openaire   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

NSUN4-mediated m5C modification of circERI3 promotes lung cancer development by altering mitochondrial energy metabolism

Cancer Letters
As a highly important methylation modification, the 5-methyladenosine (m5C) modification can profoundly affect RNAs by regulating their transcription, structure and stability. With the continuous development of high-throughput technology, differentially expressed circular RNAs (circRNAs) have been increasingly discovered, and circRNAs play unique roles
Jiaxi Wu, Qingyun Zhao, Sixian Chen, Haotian Xu, Ruirui Zhang, Dunyu Cai, Yihong Gao, Wenyi Peng, Xingcai Chen, Shengyi Yuan, Deqing Li, Gang Li, Aruo Nan   +12 more
openaire   +4 more sources

Emerging Role of RNA m5C Modification in Cardiovascular Diseases

Journal of Cardiovascular Translational Research, 2022
Epitranscriptomics is the emerging field of research that comprises the study of epigenetics changes in RNAs. Progressing development in the field of epigenetics has helped to manage and comprehend human diseases. RNA methylation regulates all aspects of RNA functions, which are involved in the pathogenesis of human diseases.
Kannan, Balachander, Jayaseelan Vijayashree, Priyadharsini, Anitha, Roy, Arumugam, Paramasivam   +3 more
openaire   +2 more sources

m5C-Seq: Machine learning-enhanced profiling of RNA 5-methylcytosine modifications

Computers in Biology and Medicine
Epigenetic modifications, particularly RNA methylation and histone alterations, play a crucial role in heredity, development, and disease. Among these, RNA 5-methylcytosine (m5C) is the most prevalent RNA modification in mammalian cells, essential for processes such as ribosome synthesis, translational fidelity, mRNA nuclear export, turnover, and ...
Zeeshan Abbas, Mobeen Ur Rehman, Hilal Tayara, Seung Won Lee, Kil To Chong   +4 more
openaire   +2 more sources

The Role of RNA m5C Modification in Central Nervous System Diseases

Discovery Medicine
As advances in RNA modification research progress, the significance of 5-methylcytosine (m5C) modification is being increasingly acknowledged. m5C undergoes modification by the methyltransferase NOP2/Sun domain (NSUN) family/DNA methyltransferase (DNMT) family (writer) and is removed by demethylases (eraser), including the ten-eleven translocation (TET)
Peiyan, Wu, Jiaxiang, Gao, Guangming, Lan, Yichao, Wang   +3 more
openaire   +2 more sources

m5C modification of LINC00324 promotes angiogenesis in glioma through CBX3/VEGFR2 pathway

International Journal of Biological Macromolecules
Angiogenesis plays a major role in tumor initiation, progression, and metastasis. This is why finding antiangiogenic targets is essential in the treatment of gliomas. In this study, NSUN2 and LINC00324 were significantly upregulated in conditionally cultured glioblastoma endothelial cells (GECs).
Aini, Pan, Yixue, Xue, Xuelei, Ruan, Weiwei, Dong, Di, Wang, Yunhui, Liu, Libo, Liu, Yang, Lin, Tiange, E, Hongda, Lin, Hailing, Xu, Xiaobai, Liu, Ping, Wang   +12 more
openaire   +2 more sources

Simultaneous profiling of ac4C and m5C modifications from nanopore direct RNA sequencing

International Journal of Biological Macromolecules
N4-acetylcytidine (ac4C) and 5-methylcytidine (m5C) play important roles in mRNA stability, translation efficiency, and cellular stress responses. Current methods for detecting RNA modifications from nanopore sequencing data do not support simultaneous de novo identification of both modifications.
You, Wu, Wenna, Shao, Shuai, Liu, Liyuan, Wang, Pengfei, Xu, Xingpeng, Zhang, Haihan, Song, Xiaofei, Li, Jian, Wang, Xiang, Yu   +9 more
openaire   +2 more sources