Results 1 to 10 of about 7,626 (175)
Clinical and Translational Medicine, 2023 Background The precise temporal and spatial regulation of N5‐methylcytosine (m5C) RNA modification plays essential roles in RNA metabolism, and is necessary for the maintenance of epigenome homeostasis.
Xianqun Fan, Xuyang Wen, Linna Lu
exaly +2 more sources
Frontiers in Immunology, 2022 Background5-Methylcytidine (m5C) methylation is an emerging epigenetic modification in recent years, which is associated with the development and progression of various cancers.
Jiangyi Wang, Jiahao Bao, Yushan Liu
exaly +3 more sources
Frontiers in Oncology, 2022 BackgroundPancreatic adenocarcinoma (PAAD) is one of the most malignant cancers and has a poor prognosis. As a critical RNA modification, 5-methylcytosine (m5C) has been reported to regulate tumor progression, including PAAD progression.
Ronglin Wang +14 more
doaj +1 more source
Frontiers in Surgery, 2023 BackgroundRecent studies have found that 5-methylcytosine (m5C) modulators are associated with the prognosis and treatment of cancer. However, the relevance of m5C modulators in sarcoma prognosis and the tumour microenvironment is unclear.MethodsWe ...
Shusheng Wu +5 more
doaj +1 more source
Frontiers in Genetics, 2022 Background: Multiple myeloma (MM) is a hematological malignancy in which plasma cells proliferate abnormally. 5-methylcytosine (m5C) methylation modification is the primary epigenetic modification and is involved in regulating the occurrence, development,
Hefei Ren +8 more
doaj +1 more source
RNA Modification in Carcinogenesis and Development of Gastric Cancer
Zhongliu Fangzhi Yanjiu, 2023 The occurrence of gastric cancer is closely related to environmental, genetic, and epigenetic factors. Currently, RNA modification is a research frontier and hotspot in the field of epigenetics.
XU Jiawen, WANG Qiang, WANG Shouyu
doaj +1 more source
Frontiers in Oncology, 2022 PurposeStudies reported that 5-methylcytosine (m5C) RNA transferase alters tumor progression; however, studies of m5C-related lncRNA remain lacking. This article intends to study the lncRNA modified by m5C RNA transferase in hepatocellular carcinoma ...
Qi Pan, Caiyu Yi, Yijie Zhang
doaj +1 more source
The potential regulatory role of RNA methylation in ovarian cancer
RNA Biology, 2023 Updates in whole genome sequencing technologies have revealed various RNA modifications in cancer, among which RNA methylation is a frequent posttranscriptional modification.
Shijie Zhao +5 more
doaj +1 more source
Transcriptome-Wide Annotation of m5C RNA Modifications Using Machine Learning
Frontiers in Plant Science, 2018 The emergence of epitranscriptome opened a new chapter in gene regulation. 5-methylcytosine (m5C), as an important post-transcriptional modification, has been identified to be involved in a variety of biological processes such as subcellular localization
Jie Song +7 more
doaj +1 more source
Characterization of BisI Homologs
Frontiers in Microbiology, 2021 BisI is a sequence-specific and 5-methylcytosine (m5C)-dependent restriction endonuclease (REase), that cleaves the modified DNA sequence Gm5CNGC (G indicates that the cytosine opposite to G is modified).
Shuang-yong Xu +7 more
doaj +1 more source