Results 41 to 50 of about 8,119 (209)

Exploration of Potential Roles of m5C-Related Regulators in Colon Adenocarcinoma Prognosis [PDF]

Frontiers in Genetics, 2022
Objectives: The purpose of this study was to investigate the role of 13 m5C-related regulators in colon adenocarcinoma (COAD) and determine their prognostic value.Methods: Gene expression and clinicopathological data were obtained from The Cancer Genome Atlas (TCGA) datasets.
Yuancheng Huang, Chaoyuan Huang, Xiaotao Jiang, Yanhua Yan, Kunhai Zhuang, Fengbin Liu, Fengbin Liu, Peiwu Li, Yi Wen   +8 more
openaire   +3 more sources

m5C Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Papillary Thyroid Carcinoma

Frontiers in Oncology, 2021
Recently, immune response modulation at the epigenetic level is illustrated in studies, but the possible function of RNA 5-methylcytosine (m5C) modification in cell infiltration within the tumor microenvironment (TME) is still unclear.
Fei Li, Qingmei Deng, Xiaoxi Pang, Shan Huang, Jingmiao Zhang, Xiaxia Zhu, Hong Chen, Xiuxia Liu   +7 more
doaj   +1 more source

Datasheet1_Modification of m5C regulators in sarcoma can guide different immune infiltrations as well as immunotherapy.docx

, 2023
BackgroundRecent studies have found that 5-methylcytosine (m5C) modulators are associated with the prognosis and treatment of cancer. However, the relevance of m5C modulators in sarcoma prognosis and the tumour microenvironment is unclear.MethodsWe ...
Yangfan Zhou (10889385), Shusheng Wu (10889388), Mengge Li (3775978), Hao Shen (195461), Yifu He (5881085), Rixin Su (14337084)   +5 more
core   +1 more source

Machine-Learning-Based m5C Score for the Prognosis Diagnosis of Osteosarcoma

Journal of Oncology, 2021
Background. Osteosarcoma is a common and highly metastatic malignant tumor, and m5C RNA methylation regulates various biological processes. The purpose of this study was to explore the prognostic role of m5C in osteosarcoma using machine learning. Methods.
Haijie Zhang, Peipei Xu, Yichang Song
openaire   +2 more sources

m5CRegpred: Epitranscriptome Target Prediction of 5-Methylcytosine (m5C) Regulators Based on Sequencing Features

, 2022
5-methylcytosine (m5C) is a common post-transcriptional modification observed in a variety of RNAs. m5C has been demonstrated to be important in a variety of biological processes, including RNA structural stability and metabolism.
Zhizhou He, Jing Xu, Shuxiang Wu, Haoran Shi   +3 more
core   +1 more source

Research advances of mRNA methylation in kidney diseases

Linchuang shenzangbing zazhi
Recently mRNA methylation modification has been extensively examined, including N6-methyladenosine (m6A), N5-methylcytidine (m5C) and N1-methyladenosine (m1A).
Shi-wen Zhang, Jun-jun Luan, Hua Zhou
doaj   +1 more source

Advances in mRNA 5-methylcytosine modifications: Detection, effectors, biological functions, and clinical relevance

Molecular Therapy: Nucleic Acids, 2021
5-methylcytosine (m5C) post-transcriptional modifications affect the maturation, stability, and translation of the mRNA molecule. These modifications play an important role in many physiological and pathological processes, including stress response ...
Gangqiang Guo, Kan Pan, Su Fang, Lele Ye, Xinya Tong, Zhibin Wang, Xiangyang Xue, Huidi Zhang   +7 more
doaj   +1 more source

Table1_Modification of m5C regulators in sarcoma can guide different immune infiltrations as well as immunotherapy.xls

, 2023
BackgroundRecent studies have found that 5-methylcytosine (m5C) modulators are associated with the prognosis and treatment of cancer. However, the relevance of m5C modulators in sarcoma prognosis and the tumour microenvironment is unclear.MethodsWe ...
Yangfan Zhou (10889385), Shusheng Wu (10889388), Mengge Li (3775978), Hao Shen (195461), Yifu He (5881085), Rixin Su (14337084)   +5 more
core   +1 more source

Integrative 5-Methylcytosine Modification Immunologically Reprograms Tumor Microenvironment Characterizations and Phenotypes of Clear Cell Renal Cell Carcinoma

Frontiers in Cell and Developmental Biology, 2021
The tumor microenvironment (TME) affects the biologic malignancy of clear cell renal cell carcinoma (ccRCC). The influence of the 5-methylcytosine (m5C) epigenetic modification on the TME is unknown.
Wenhao Xu, Wenhao Xu, Wenkai Zhu, Wenkai Zhu, Xi Tian, Xi Tian, Wangrui Liu, Yuanyuan Wu, Aihetaimujiang Anwaier, Aihetaimujiang Anwaier, Jiaqi Su, Jiaqi Su, Shiyin Wei, Yuanyuan Qu, Yuanyuan Qu, Hailiang Zhang, Hailiang Zhang, Dingwei Ye, Dingwei Ye   +18 more
doaj   +1 more source

The lncRNA epigenetics: The significance of m6A and m5C lncRNA modifications in cancer

Frontiers in Oncology, 2023
Most of our transcribed RNAs are represented by non-coding sequences. Long non-coding RNAs (lncRNAs) are transcripts with no or very limited protein coding ability and a length >200nt. They can be epigenetically modified. N6-methyladenosine (m6A), N1-methyladenosine (m1A), 5-methylcytosine (m5C), 7-methylguanosine (m7G) and 2’-O-methylation (Nm)
Vincenza Ylenia Cusenza, Annalisa Tameni, Antonino Neri, Raffaele Frazzi   +3 more
openaire   +3 more sources