Results 51 to 60 of about 11,326 (215)

Topological Characterization of Human and Mouse m5C Epitranscriptome Revealed by Bisulfite Sequencing

International Journal of Genomics, 2018
Background. Compared with the well-studied 5-methylcytosine (m5C) in DNA, the role and topology of epitranscriptome m5C remain insufficiently characterized. Results.
Zhen Wei, Subbarayalu Panneerdoss, Santosh Timilsina, Jingting Zhu, Tabrez A. Mohammad, Zhi-Liang Lu, João Pedro de Magalhães, Yidong Chen, Rong Rong, Yufei Huang, Manjeet K. Rao, Jia Meng   +11 more
doaj   +1 more source

Formation and abundance of 5-hydroxymethylcytosine in RNA. [PDF]

, 2015
RNA methylation is emerging as a regulatory RNA modification that could have important roles in the control and coordination of gene transcription and protein translation. Herein, we describe an in vivo isotope-tracing methodology to demonstrate that the
Bachman, Martin, Balasubramanian, Shankar, Huber, Sabrina M, Mendil, Lee, Miska, Eric A, Smollett, Katherine, van Delft, Pieter, Werner, Finn   +7 more
core   +2 more sources

Biological functions of 5-methylcytosine RNA-binding proteins and their potential mechanisms in human cancers

Frontiers in Oncology
The 5-methylcytosine (m5C) modification is a crucial epigenetic RNA modification, which is involved in the post-transcriptional regulation of genes. It plays an important role in various biological processes, including cell metabolism, growth, apoptosis,
Tingting Zhao, Zhe Zhang, Zhuo Chen, Guozheng Xu, Yongxi Wang, Fang Wang   +5 more
doaj   +1 more source

Can Protostellar Jets Drive Supersonic Turbulence in Molecular Clouds?

, 2007
Jets and outflows from young stellar objects are proposed candidates to drive supersonic turbulence in molecular clouds. Here, we present the results from multi-dimensional jet simulations where we investigate in detail the energy and momentum deposition
Blandford R. D., Christian Fendt, Downes T. P., Gueth F., Henney W. J., Klessen R. S., Knee L. B. G., Micono M., Mundt R., O'Sullivan S., Raga A. C., Ralf S. Klessen, Robi Banerjee, Smith M. D., Warin S.   +14 more
core   +1 more source

Integrative 5-Methylcytosine Modification Immunologically Reprograms Tumor Microenvironment Characterizations and Phenotypes of Clear Cell Renal Cell Carcinoma

Frontiers in Cell and Developmental Biology, 2021
The tumor microenvironment (TME) affects the biologic malignancy of clear cell renal cell carcinoma (ccRCC). The influence of the 5-methylcytosine (m5C) epigenetic modification on the TME is unknown.
Wenhao Xu, Wenhao Xu, Wenkai Zhu, Wenkai Zhu, Xi Tian, Xi Tian, Wangrui Liu, Yuanyuan Wu, Aihetaimujiang Anwaier, Aihetaimujiang Anwaier, Jiaqi Su, Jiaqi Su, Shiyin Wei, Yuanyuan Qu, Yuanyuan Qu, Hailiang Zhang, Hailiang Zhang, Dingwei Ye, Dingwei Ye   +18 more
doaj   +1 more source

Optical Readout in a Multi-Module System Test for the ATLAS Pixel Detector

, 2005
The innermost part of the ATLAS experiment at the LHC, CERN, will be a pixel detector. The command messages and the readout data of the detector are transmitted over an optical data path.
Chu, Jennifer Richter, Joachim Schultes, Karl-Heinz Becks, Kendall Reeves, Peter Gerlach, Peter Mättig, Simon Nderitu Kirichu, Susanne Kersten, Tobias Flick   +9 more
core   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

The Bipartite Structure of the tRNA m\u3csup\u3e1\u3c/sup\u3eA58 Methyltransferase from \u3cem\u3eS. cerevisiae\u3c/em\u3e is Conserved in Humans [PDF]

, 2005
Among all types of RNA, tRNA is unique given that it possesses the largest assortment and abundance of modified nucleosides. The methylation at N1 of adenosine 58 is a conserved modification, occurring in bacterial, archaeal, and eukaryotic tRNAs. In the
Andersland, Joshua, Anderson, James T., Krecic, Annette M., Ozanick, Sarah G.   +3 more
core   +1 more source

Fluctuations and Landau-Devonshire expansion for barium titanate

, 2002
The experimentally observed temperature dependence of the quartic coefficients in the Landau-Devonshire expansion for BaTiO_3 is naturally accounted for within a proper fluctuation model.
Sokolov, A. I., Tagantsev, A. K.
core   +1 more source

Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3. [PDF]

, 2016
Epitranscriptome modifications are required for structure and function of RNA and defects in these pathways have been associated with human disease.
Blanco, Sandra, Dietmann, Sabine, Durbin, Richard, Frye, Michaela, Hoffmann, Georg F, Hussain, Shobbir, Kolb-Kokocinski, Anja, Kotzaeridou, Urania, Kremer, Laura, Lantaff, Rebecca, Mayr, Johannes A, Memari, Yasin, Minczuk, Michal, Pearce, Sarah F, Powell, Christopher A, Prokisch, Holger, Rorbach, Joanna, Sauer, Sascha, Van Haute, Lindsey   +18 more
core   +4 more sources