Results 1 to 10 of about 564,596 (305)
RNA Modification in Metabolism [PDF]
MedCommEpigenetic regulation in disease development has been witnessed within this decade. RNA methylation is the predominant form of epigenetic regulation, and the most prevalent modification in RNA is N6‐methyladenosine (m6A).
Yadi Liu +4 more
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Assessment of nanopore RNA modification calling in human cell lines and synthetic systems [PDF]
Genome BiologyBackground Nanopore technology enables the direct sequencing of intact RNA molecules allowing for the detection of native chemical modifications. In 2024, Oxford Nanopore Technologies updated direct RNA sequencing from RNA002 to RNA004 platform as well ...
Neda Ghohabi Esfahani +6 more
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RNA modification mapping with JACUSA2 [PDF]
Genome Biology, 2022 Several high-throughput antibody-free methods for RNA modification detection from sequencing data have been developed. We present JACUSA2 as a versatile software solution and comprehensive analysis framework for RNA modification detection assays that are
Michael Piechotta +4 more
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GlycoRNA, a novel RNA modification [PDF]
Discover OncologyRNA plays a variety of critical roles in cellular environments, including serving as a structural molecule, messenger molecule, translational carrier, and effector molecule.
Binbin Hu +4 more
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Cancer Management and Research, 2022 Zhiyuan Yang,1,2,* Siyu Zhang,1,2,* Tian Xia,1,2,* Yue Fan,1,2 Ying Shan,1,2 Kaiwen Zhang,1,2 Jiayan Xiong,1,2 Miao Gu,1,2 Bo You1,2 1Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Medical ...
Yang Z +8 more
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Regulatory role and mechanism of m6A RNA modification in human metabolic diseases
Molecular Therapy: Oncolytics, 2021 Metabolic diseases caused by disorders in amino acids, glucose, lipid metabolism, and other metabolic risk factors show high incidences in young people, and current treatments are ineffective.
Yuliang Zhang +8 more
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Comprehensive mapping of RNA modification dynamics and crosstalk via deep learning and nanopore direct RNA-sequencing [PDF]
Nature CommunicationsDespite the extensive studies of individual RNA modifications, the lack of methods to detect multiple modification types simultaneously has left the global epitranscriptomic landscape and its underlying crosstalk largely unexplored. Here, we present ORCA
Han Dong +6 more
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m5C RNA modification in gastrointestinal cancers: a comprehensive review from molecular mechanism to clinical implication [PDF]
Biology Direct5-methylcytosine (m5C) modification has emerged as a novel epigenetic modification of ribonucleic acids (RNAs), encompassing messenger RNAs (mRNAs) and non- coding RNAs, in recent years.
Chao Xu, Qinwen Ye, Hao Wang, Yue Yu
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The RNA modification database--1998 [PDF]
Nucleic Acids Research, 1998 The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from RNA, and is maintained as an updated version of the initial printed report [Limbach,P.A., Crain,P.F. and McCloskey,J.A. (1994) Nucleic Acids Res. , 22, 2183-2196].
James A. McCloskey, Pamela F. Crain
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RNA Modification and Its Implication in Plant Pathogenic Fungi [PDF]
The Plant Pathology Journal, 2021 Interaction of a pathogen with its host plant requires both flexibility and rapid shift in gene expression programs in response to environmental cues associated with host cells. Recently, a growing volume of data on the diversity and ubiquity of internal
Junhyun Jeon, Song Hee Lee
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