Results 1 to 10 of about 258,822 (114)

Roles of RNA Methylation on Tumor Immunity and Clinical Implications

Frontiers in Immunology, 2021
RNA methylation is a kind of RNA modification that exists widely in eukaryotes and prokaryotes. RNA methylation occurs not only in mRNA but also in ncRNA.
Maorun Zhang, Junmin Song, Weitang Yuan, Wei Zhang, Zhenqiang Sun, Zhenqiang Sun   +5 more
doaj   +3 more sources

RNA methylation in plants: An overview

Frontiers in Plant Science, 2023
RNA methylation is an important post-transcriptional modification that influences gene regulation. Over 200 different types of RNA modifications have been identified in plants.
Harshraj Shinde, Ambika Dudhate, Ulhas S. Kadam, Jong Chan Hong, Jong Chan Hong   +4 more
doaj   +3 more sources

Advances in research on RNA methylation and cancer radiotherapy resistance [PDF]

Frontiers in Oncology
RNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions.
Hui Liu, Hui Luo, Ming Jin, Zhen Zheng, Yang Xi, Kaitai Liu   +5 more
doaj   +2 more sources

RNA methylation in urological cancers: regulatory logic, biological functions, and clinical relevance [PDF]

Frontiers in Immunology
Urological malignancies, including prostate, bladder, and renal cancers, remain a major clinical challenge because of tumor heterogeneity, disease progression, and therapeutic resistance.
Jiahao Peng, Chong Xie, Zhangmin Xie, Feng Tang, Zhiying Wang, Minhao Liu, Li Yu, Chenhao Tang, Ziyang Liu, Zuowei Yuan, Longwei Liao, Xinpan Zou, Xuran Liu, Mingyang Yi, Huangheng Tao, Wei Wei, Tao Liu, Yixiang Liao   +17 more
doaj   +2 more sources

Regulation of RNA methylation linked to drug resistance in gastric cancer [PDF]

Frontiers in Cell and Developmental Biology
In global terms, gastric cancer (GC) represents one of the most commonly occurring malignancies. It is positioned as the fifth most frequent cancer in terms of incidence and stands as the third primary contributor to cancer-related mortality.
Zihan Yang, Yanpin Ma, Ziyi Xu, Hongyan Liu, Xinyu Gu, Jiachun Sun   +5 more
doaj   +2 more sources

m6A RNA methylation modulates IFN-γ-stimulated intestinal epithelial cell-intrinsic antiparasitic defense. [PDF]

PLoS Pathogens
N6-methyladenosine (m6A) RNA methylation is one of the most prevalent reversible post-transcriptional RNA modifications and has been recognized as a crucial regulator of host immune responses.
Chansorena Pok, Ai-Yu Gong, Marion L Graham, Shuhong Wang, Silu Deng, Zinat Sharmin, Eugene Lu, Guoqing Lu, Chuan He, Xian-Ming Chen   +9 more
doaj   +2 more sources

Construction and validation of m6A RNA methylation regulators associated prognostic model for gastrointestinal cancer

IET Systems Biology, 2022
N6‐methyladenosine (m6A) RNA methylation is correlated with carcinogenesis and dynamically possessed through the m6A RNA methylation regulators. This paper aimed to explore 13 m6A RNA methylation regulators' role in gastrointestinal cancer (GIC) and ...
Yandong Miao, Bin Su, Xiaolong Tang, Jiangtao Wang, Wuxia Quan, Yonggang Chen, Denghai Mi   +6 more
doaj   +1 more source

Effects of RNA methylation on Tumor angiogenesis and cancer progression

Molecular Cancer, 2023
Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA methylation is one of the most common modifications and is widely observed in eukaryotes and prokaryotes. Accumulating studies have revealed that RNA methylation affects the
Mingyu Han, Haifeng Sun, Quanbo Zhou, Jinbo Liu, Junhong Hu, Weitang Yuan, Zhenqiang Sun   +6 more
doaj   +1 more source

CUCUME: An RNA methylation database integrating systemic mRNAs signals, GWAS and QTL genetic regulation and epigenetics in different tissues of Cucurbitaceae

Computational and Structural Biotechnology Journal, 2023
As an internal modification of transcripts, RNA methylation determines RNA fate by changing RNA–protein binding affinity. In plants, RNA methylation is ubiquitous and is involved in all aspects of RNA post-transcriptional regulation.
Xiaojun Li, Shujin Lin, Chenggang Xiang, Wenqian Liu, Xiaojing Zhang, Cuicui Wang, Xiaohong Lu, Mengshuang Liu, Tao Wang, Zixi Liu, Naonao Wang, Lihong Gao, Xiao Han, Wenna Zhang   +13 more
doaj   +1 more source

Role of Main RNA Methylation in Hepatocellular Carcinoma: N6-Methyladenosine, 5-Methylcytosine, and N1-Methyladenosine

Frontiers in Cell and Developmental Biology, 2021
RNA methylation is considered a significant epigenetic modification, a process that does not alter gene sequence but may play a necessary role in multiple biological processes, such as gene expression, genome editing, and cellular differentiation.
Yating Xu, Yating Xu, Yating Xu, Yating Xu, Menggang Zhang, Menggang Zhang, Menggang Zhang, Menggang Zhang, Qiyao Zhang, Qiyao Zhang, Qiyao Zhang, Qiyao Zhang, Xiao Yu, Xiao Yu, Xiao Yu, Xiao Yu, Zongzong Sun, Yuting He, Yuting He, Yuting He, Yuting He, Wenzhi Guo, Wenzhi Guo, Wenzhi Guo, Wenzhi Guo   +24 more
doaj   +1 more source