Results 31 to 40 of about 248,618 (295)
Predicting genes associated with RNA methylation pathways using machine learning.
, 2022 RNA methylation plays an important role in functional regulation of RNAs, and has thus attracted an increasing interest in biology and drug discovery.
Santos-Rosa, Helena +7 more
core +2 more sources
Role of m6A RNA Methylation in Thyroid Cancer Cell Lines [PDF]
, 2022 N6-methyladenosine (m6A) is the most abundant internal modification of RNA in eukaryotic cells, and, in recent years, it has gained increasing attention.
Baldan F. +4 more
core +2 more sources
RNA‐binding proteins and RNA methylation in myeloid cells
Immunological Reviews, 2021 AbstractRNA‐binding proteins (RBPs) regulate all aspects of the life of mRNA transcripts. They are critically important in regulating immune responses, most notably by restraining excessive inflammation that can potentially lead to tissue damage.
Marian Bataclan +2 more
openaire +3 more sources
RNA methylation during epigenetic reprogramming [PDF]
, 2020 Biologically derived, chemically-modified RNA molecules represent a ubiquitously present but poorly understood area of molecular biology. Despite this substantive gap in our understanding RNA methyltransferase (RNMT) enzymes, which catalyse the ...
Hudson, Karl David
core +1 more source
PLOS Genetics, 2020 RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM pathway is unique to plants, although other mechanisms of RNA-directed chromatin modification have also been described in fungi and animals.
Robert M. Erdmann, Colette L. Picard
openaire +4 more sources
The role of RNA m6A methylation in lipid metabolism
Frontiers in Endocrinology, 2022 The m6A methylation is the most numerous modification of mRNA in mammals, coordinated by RNA m6A methyltransferases, RNA m6A demethylases, and RNA m6A binding proteins. They change the RNA m6A methylation level in their specific manner.
Yuting Wang +5 more
doaj +1 more source
RNA-directed DNA methylation [PDF]
Current Opinion in Plant Biology, 2011 DNA methylation is an important epigenetic mechanism for silencing transposons and other repetitive elements, and for stable repression of specific transgenes and endogenous genes. Plants can utilize small interfering RNAs (siRNAs) to guide de novo DNA methyltransferases for the establishment of sequence-specific DNA methylation.
Huiming, Zhang, Jian-Kang, Zhu
openaire +2 more sources
Myo1e overexpression in lung adenocarcinoma is associated with increased risk of mortality
Scientific Reports, 2023 This study aims to perform a comprehensive genomic analysis to assess the influence of overexpression of MYO1E in non-small cell lung carcinoma (NSCLC) and whether there are differences in survival and mortality risk in NSCLC patients depending on both ...
Ignacio Jusue-Torres +21 more
doaj +1 more source
Detection and analysis of RNA methylation [PDF]
F1000Research, 2019 Our understanding of the expanded genetic alphabet has been growing rapidly over the last two decades, and many of these developments came more than 80 years after the original discovery of a modified guanine in tuberculosis DNA. These new understandings, leading to the field of epigenetics, have led to exciting new fundamental and applied knowledge ...
Nigel P. Mongan +2 more
openaire +2 more sources
Journal of Inflammation Research, 2022 Xin-Yu Li,1,2 Xi-Tao Yang1 1Department of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Department of Neurosurgery, Shanghai ...
Li XY, Yang XT
doaj