Results 1 to 10 of about 26,465 (226)

M1a prostate cancer: Results of a Dutch multidisciplinary consensus meeting

open access: yesBJUI Compass, 2021
Objectives To determine the consensus of a Dutch multidisciplinary expert panel on the diagnostic evaluation and treatment of de novo and recurrent metastatic prostate cancer (PCa) limited to non‐regional lymph nodes (M1a) in daily clinical practice ...
Shafak Aluwini   +7 more
doaj   +3 more sources

N1-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction

open access: yesCell Death Discovery, 2023
N1-Methyladenosine (m1A) is an abundant modification of transcripts, plays important roles in regulating mRNA structure and translation efficiency, and is dynamically regulated under stress.
Zhangyang Qi   +12 more
doaj   +1 more source

Effect of Lymph Node Metastasis on Prognosis of Small Cell Lung Cancer with M1a Disease: A Study Based on SEER database

open access: yesZhongliu Fangzhi Yanjiu, 2022
Objective To investigate the impact of lymph node metastasis on the survival of SCLC patients with M1a disease. Methods We retrospectively analyzed the medical records of 7027 SCLC patients with M1a disease from 2004 to 2015 in SEER database.
YANG Hao, MEI Tonghua
doaj   +1 more source

m1A Regulatory gene signatures are associated with certain immune cell compositions of the tumor microenvironment and predict survival in kidney renal clear cell carcinoma

open access: yesEuropean Journal of Medical Research, 2023
Adenosine N1 methylation (m1A) of RNA, a type of post-transcriptional modification, has been shown to play a significant role in the progression of cancer.
Linjun Zhou   +3 more
doaj   +1 more source

An m6A/m5C/m1A/m7G-Related Long Non-coding RNA Signature to Predict Prognosis and Immune Features of Glioma

open access: yesFrontiers in Genetics, 2022
Background: Gliomas are the most common and fatal malignant type of tumor of the central nervous system. RNA post-transcriptional modifications, as a frontier and hotspot in the field of epigenetics, have attracted increased attention in recent years ...
Dongqi Shao   +6 more
doaj   +1 more source

Generalized symplectic symmetric spaces [PDF]

open access: yes, 2013
Bielavsky introduced and investigated the class of symmetric symplectic spaces, that is, symmetric spaces endowed with a symplectic form invariant with respect to symmetries.
Bochenski, Maciej, Tralle, Aleksy
core   +2 more sources

The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome

open access: yesJournal of Inflammation Research, 2023
Haishi Zheng,1,2 Yirixiati Aihaiti,2 Yongsong Cai,2 Qiling Yuan,2 Mingyi Yang,2 Zheng Li,2 Ke Xu,2 Peng Xu1,2 1Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Department of Joint ...
Zheng H   +7 more
doaj  

The Prognostic Value and Immune Landscapes of a m6A/m5C/m1A-Related LncRNAs Signature in Head and Neck Squamous Cell Carcinoma

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: N6-methyladenosine (m6A), 5-methylcytosine (m5C) and N1-methyladenosine (m1A) are the main RNA methylation modifications involved in the progression of cancer.
Enhao Wang   +7 more
doaj   +1 more source

RNA N1-methyladenosine regulator-mediated methylation modification patterns and heterogeneous signatures in glioma

open access: yesFrontiers in Immunology, 2022
N1-methyladenosine (m1A) is ubiquitous in eukaryotic RNA and regulates mRNA translation. However, little is known about its regulatory role in glioma. Here, we identified 4 m1A modification-related patterns based on m1A regulators in the TCGA (The Cancer
Meng Mao   +8 more
doaj   +1 more source

m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer

open access: yesTranslational Oncology, 2019
BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification.
Yueshui Zhao   +17 more
doaj   +1 more source

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