Results 21 to 30 of about 11,313 (179)

Comprehensive of N1-Methyladenosine Modifications Patterns and Immunological Characteristics in Ovarian Cancer

Frontiers in Immunology, 2021
Backgroundrecently, many researches have concentrated on the relevance between N1-methyladenosine (m1A) methylation modifications and tumor progression and prognosis.
Jinhui Liu, Can Chen, Yichun Wang, Cheng Qian, Junting Wei, Yan Xing, Jianling Bai   +6 more
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M1a/M1b esophageal carcinoma: Clinical relevance [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 1999
The 1997 staging system for esophageal carcinoma subdivides distant metastatic disease (M1) into M1a (nonregional lymph node metastases) and M1b (other metastases). This study evaluates the relevance of this classification.One hundred forty patients were identified with M1 disease, 36 (26%) M1a and 104 (74%) M1b.
Christie, Neil A., Rice, Thomas W., DeCamp, Malcolm M., Goldblum, John R., Adelstein, David J., Zuccaro, Gregory, Rybicki, Lisa A., Blackstone, Eugene H.   +7 more
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Genetic characteristics and prognostic implications of m1A regulators in pancreatic cancer [PDF]

Bioscience Reports, 2021
Abstract Studies have identified the methylation of N1 adenosine (m1A), an RNA modification, playing an important role in the progression of the tumorigenesis. The present study aimed to analyze the genetic characteristics and prognostic value of m1A regulators in pancreatic cancer.
Qingyuan Zheng, Xiao Yu, Qiyao Zhang, Yuting He, Wenzhi Guo   +4 more
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M1ARegpred: Epitranscriptome Target Prediction of N1-methyladenosine (m1A) Regulators Based on Sequencing Features and Genomic Features

Frontiers in Bioscience-Landmark, 2022
Background: N1-methyladenosine (m1A) is a reversible post-transcriptional modification in mRNA, which has been proved to play critical roles in various biological processes through interaction with different m1A regulators.
Jia-Hui Yao, Meng-Xian Lin, Wen-Jun Liao, Wei-Jie Fan, Xiao-Xin Xu, Haoran Shi, Shu-Xiang Wu   +6 more
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Cytoplasmic m1A reader YTHDF3 inhibits trophoblast invasion by downregulation of m1A-methylated IGF1R [PDF]

Cell Discovery, 2020
AbstractN1-methyladenosine (m1A) is one of the important post-transcriptional modifications in RNA and plays an important role in promoting translation or decay of m1A-methylated messenger RNA (mRNA), but the “reader” protein and the exact biological role of m1A remain to be determined.
Qingliang Zheng, Haili Gan, Fenglian Yang, Yongli Yao, Fan Hao, Ling Hong, Liping Jin   +6 more
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Reversible RNA Modification N1-methyladenosine (m1A) in mRNA and tRNA

Genomics, Proteomics & Bioinformatics, 2018
More than 100 modifications have been found in RNA. Analogous to epigenetic DNA methylation, epitranscriptomic modifications can be written, read, and erased by a complex network of proteins.
Chi Zhang, Guifang Jia
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Gene Expression Profile of RNA N1-methyladenosine methyltransferases [PDF]

E3S Web of Conferences, 2020
N1-methyladenosine (m1A) is a kind of common and abundant methylation modification in eukaryotic mRNA and long-chain non-coding RNA. Nucleoside methyltransferase (MTase) of m1A is a diverse protein family, which is characterized by the presence of ...
Rao Mingzhu
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The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome

Journal of Inflammation Research, 2023
Haishi Zheng,1,2 Yirixiati Aihaiti,2 Yongsong Cai,2 Qiling Yuan,2 Mingyi Yang,2 Zheng Li,2 Ke Xu,2 Peng Xu1,2 1Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Department of Joint ...
Zheng H, Aihaiti Y, Cai Y, Yuan Q, Yang M, Li Z, Xu K, Xu P   +7 more
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N1-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction

Cell Death Discovery, 2023
N1-Methyladenosine (m1A) is an abundant modification of transcripts, plays important roles in regulating mRNA structure and translation efficiency, and is dynamically regulated under stress.
Zhangyang Qi, Chi Zhang, Huan Jian, Mengfan Hou, Yongfu Lou, Yi Kang, Wei Wang, Yigang Lv, Shenghui Shang, Chaoyu Wang, Xueying Li, Shiqing Feng, Hengxing Zhou   +12 more
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m1A Regulatory gene signatures are associated with certain immune cell compositions of the tumor microenvironment and predict survival in kidney renal clear cell carcinoma

European Journal of Medical Research, 2023
Adenosine N1 methylation (m1A) of RNA, a type of post-transcriptional modification, has been shown to play a significant role in the progression of cancer.
Linjun Zhou, Weidong Zhou, Yuan Li, Ruifang Hua   +3 more
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