Results 1 to 10 of about 237 (128)

Gene Expression Profile of RNA N1-methyladenosine methyltransferases [PDF]

E3S Web of Conferences, 2020
N1-methyladenosine (m1A) is a kind of common and abundant methylation modification in eukaryotic mRNA and long-chain non-coding RNA. Nucleoside methyltransferase (MTase) of m1A is a diverse protein family, which is characterized by the presence of ...
Rao Mingzhu
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Role of Main RNA Methylation in Hepatocellular Carcinoma: N6-Methyladenosine, 5-Methylcytosine, and N1-Methyladenosine [PDF]

Frontiers in Cell and Developmental Biology, 2021
RNA methylation is considered a significant epigenetic modification, a process that does not alter gene sequence but may play a necessary role in multiple biological processes, such as gene expression, genome editing, and cellular differentiation.
Yating Xu, Yating Xu, Yating Xu, Yating Xu, Menggang Zhang, Menggang Zhang, Menggang Zhang, Menggang Zhang, Qiyao Zhang, Qiyao Zhang, Qiyao Zhang, Qiyao Zhang, Xiao Yu, Xiao Yu, Xiao Yu, Xiao Yu, Zongzong Sun, Yuting He, Yuting He, Yuting He, Yuting He, Wenzhi Guo, Wenzhi Guo, Wenzhi Guo, Wenzhi Guo   +24 more
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Comprehensive of N1-Methyladenosine Modifications Patterns and Immunological Characteristics in Ovarian Cancer [PDF]

Frontiers in Immunology, 2021
Backgroundrecently, many researches have concentrated on the relevance between N1-methyladenosine (m1A) methylation modifications and tumor progression and prognosis.
Jinhui Liu, Can Chen, Yichun Wang, Cheng Qian, Junting Wei, Yan Xing, Jianling Bai   +6 more
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Research progress of N1-methyladenosine RNA modification in cancer

Cell Communication and Signaling
N1-methyladenosine (m1A) is a post-transcriptionally modified RNA molecule that plays a pivotal role in the regulation of various biological functions and activities. Especially in cancer cell invasion, proliferation and cell cycle regulation.
Yafeng Liu, Shujun Zhang, Xiaohui Gao, Yi Ru, Xinyu Gu, Xinjun Hu   +5 more
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N1-methyladenosine methylation-related metabolic genes signature and subtypes for predicting prognosis and immune microenvironment in osteosarcoma

Frontiers in Genetics, 2022
N1-methyladenosine methylation (m1A), as an important RNA methylation modification, regulates the development of many tumours. Metabolic reprogramming is one of the important features of tumour cells, and it plays a crucial role in tumour development and
Guowei Wang, Hongyi Wang, Sha Cheng, Xiaobo Zhang, Wanjiang Feng, Pan Zhang, Jianlong Wang   +6 more
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Epitranscriptomic Stability—Variable Extents of N1-Methyladenosine to N6-Methyladenosine Conversion Under Different Experimental Conditions

Biomolecules
The growing interest in epitranscriptomes has emphasized the need for accurate quantification of RNA modifications. However, the stability of RNA modifications under different experimental conditions remains poorly characterized. In this study, we use N1-
Frank Morales Shnaider, Hasna Kanan, Shrikant Patel, Norman H. L. Chiu   +3 more
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TRMT6‐Mediated m1A Modification of CDK9 mRNA is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide, with hepatitis B virus (HBV) infection being the major risk factor. Dysregulation of mRNA methylation contributes to tumorigenesis and virus replication. However, the association of N1‐
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
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Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science
Mitochondrial RNA N1‐methyladenosine (m1A) is a prevalent and reversible epitranscriptomic modification. While the biological roles of cytosolic m1A have been increasingly understood, the causal relationship between site‐specific mitochondrial m1A and ...
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
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MFAP2, upregulated by m1A methylation, promotes colorectal cancer invasiveness via CLK3

Cancer Medicine, 2023
Background Distant metastasis is the main cause of mortality in colorectal cancer (CRC) patients. N1‐methyladenosine (m1A) is a type of epitranscriptome modification.
Meng Xue, Shuyi Mi, Zizhen Zhang, Hao Wang, Wenwen Chen, Wei Wei, Guochun Lou   +6 more
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Sequencing methods and functional decoding of mRNA modifications

Fundamental Research, 2023
More than 160 types of post-transcriptional RNA modifications have been reported; there is substantial variation in modification type, abundance, site, and function across species, tissues, and RNA type.
Kai Li, Jinying Peng, Chengqi Yi
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