Genetic characteristics and prognostic implications of m1A regulators in pancreatic cancer [PDF]
Bioscience Reports, 2021 Abstract Studies have identified the methylation of N1 adenosine (m1A), an RNA modification, playing an important role in the progression of the tumorigenesis. The present study aimed to analyze the genetic characteristics and prognostic value of m1A regulators in pancreatic cancer.
Qingyuan Zheng +4 more
openaire +2 more sources
Image_2_Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung Adenocarcinoma.tif [PDF]
, 2022 BackgroundPrevious studies have demonstrated that transcriptional RNA methyladenosine modification significantly affects tumor initiation and progression.
Yifang Xiang (12698255) +6 more
core +1 more source
Image_1_Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung Adenocarcinoma.tif [PDF]
, 2022 BackgroundPrevious studies have demonstrated that transcriptional RNA methyladenosine modification significantly affects tumor initiation and progression.
Yifang Xiang (12698255) +6 more
core +1 more source
Image_4_Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung Adenocarcinoma.tif [PDF]
, 2022 BackgroundPrevious studies have demonstrated that transcriptional RNA methyladenosine modification significantly affects tumor initiation and progression.
Yifang Xiang (12698255) +6 more
core +1 more source
Image_3_Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung Adenocarcinoma.tif [PDF]
, 2022 BackgroundPrevious studies have demonstrated that transcriptional RNA methyladenosine modification significantly affects tumor initiation and progression.
Yifang Xiang (12698255) +6 more
core +1 more source
Image_3_A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma.tif [PDF]
, 2022 RNA methylation plays crucial roles in gene expression and has been indicated to be involved in tumorigenesis, while it is still unclear whether m1A modifications have potential roles in the prognosis of hepatocellular carcinoma (HCC).
Mingxing Zhao (3707557) +2 more
core +1 more source
m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation. Boo et al. [PDF]
, 2022 N6-methyladenosine (m6A), the most abundant internal mRNA modification, affects multiple steps in gene expression. Mechanistically, the binding of YTHDF2 to m6A on mRNAs elicits rapid mRNA degradation by either deadenylation via the CCR4-NOT complex or ...
Boo, S
core +3 more sources
Frontiers in Bioscience-Landmark, 2022 Background: N1-methyladenosine (m1A) is a reversible post-transcriptional modification in mRNA, which has been proved to play critical roles in various biological processes through interaction with different m1A regulators.
Jia-Hui Yao +6 more
doaj +1 more source
Image_2_A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma.tif [PDF]
, 2022 RNA methylation plays crucial roles in gene expression and has been indicated to be involved in tumorigenesis, while it is still unclear whether m1A modifications have potential roles in the prognosis of hepatocellular carcinoma (HCC).
Mingxing Zhao (3707557) +2 more
core +1 more source
Cytoplasmic m1A reader YTHDF3 inhibits trophoblast invasion by downregulation of m1A-methylated IGF1R [PDF]
Cell Discovery, 2020 AbstractN1-methyladenosine (m1A) is one of the important post-transcriptional modifications in RNA and plays an important role in promoting translation or decay of m1A-methylated messenger RNA (mRNA), but the “reader” protein and the exact biological role of m1A remain to be determined.
Qingliang Zheng +6 more
openaire +2 more sources