Results 51 to 60 of about 13,010 (203)

An m6A/m5C/m1A/m7G-Related Long Non-coding RNA Signature to Predict Prognosis and Immune Features of Glioma

Frontiers in Genetics, 2022
Background: Gliomas are the most common and fatal malignant type of tumor of the central nervous system. RNA post-transcriptional modifications, as a frontier and hotspot in the field of epigenetics, have attracted increased attention in recent years ...
Dongqi Shao, Yu Li, Junyong Wu, Binbin Zhang, Shan Xie, Xialin Zheng, Zhiquan Jiang   +6 more
doaj   +1 more source

Image_2_A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma.tif

, 2022
RNA methylation plays crucial roles in gene expression and has been indicated to be involved in tumorigenesis, while it is still unclear whether m1A modifications have potential roles in the prognosis of hepatocellular carcinoma (HCC).
Mingxing Zhao (3707557), Chen Xue (699418), Shen Shen (3509270)   +2 more
core   +1 more source

m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation. Boo et al.

, 2022
N6-methyladenosine (m6A), the most abundant internal mRNA modification, affects multiple steps in gene expression. Mechanistically, the binding of YTHDF2 to m6A on mRNAs elicits rapid mRNA degradation by either deadenylation via the CCR4-NOT complex or ...
Boo, S
core   +2 more sources

RNA m1A Methyltransferase TRMT6 Predicts Poorer Prognosis and Promotes Malignant Behavior in Glioma

Frontiers in Molecular Biosciences, 2021
Background: Glioma is the most prevalent central nervous system tumor in humans, and its prognosis remains unsatisfactory due to a lack of effective therapeutic targets.
Beibei Wang, Lihua Niu, Zhengyang Wang, Zhihua Zhao   +3 more
doaj   +1 more source

Image_3_A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma.tif

, 2022
RNA methylation plays crucial roles in gene expression and has been indicated to be involved in tumorigenesis, while it is still unclear whether m1A modifications have potential roles in the prognosis of hepatocellular carcinoma (HCC).
Mingxing Zhao (3707557), Chen Xue (699418), Shen Shen (3509270)   +2 more
core   +1 more source

Image_1_A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma.tif

, 2022
RNA methylation plays crucial roles in gene expression and has been indicated to be involved in tumorigenesis, while it is still unclear whether m1A modifications have potential roles in the prognosis of hepatocellular carcinoma (HCC).
Mingxing Zhao (3707557), Chen Xue (699418), Shen Shen (3509270)   +2 more
core   +1 more source

m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer

Translational Oncology, 2019
BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification.
Yueshui Zhao, Qijie Zhao, Parham Jabbarzadeh Kaboli, Jing Shen, Mingxing Li, Xu Wu, Jianhua Yin, Hanyu Zhang, Yuanlin Wu, Ling Lin, Lingling Zhang, Lin Wan, Qinglian Wen, Xiang Li, Chi Hin Cho, Tao Yi, Jing Li, Zhangang Xiao   +17 more
doaj   +1 more source

The Prognostic Value and Immune Landscapes of a m6A/m5C/m1A-Related LncRNAs Signature in Head and Neck Squamous Cell Carcinoma

Frontiers in Cell and Developmental Biology, 2021
Background: N6-methyladenosine (m6A), 5-methylcytosine (m5C) and N1-methyladenosine (m1A) are the main RNA methylation modifications involved in the progression of cancer.
Enhao Wang, Yang Li, Ruijie Ming, Jiahui Wei, Peiyu Du, Peng Zhou, Shimin Zong, Hongjun Xiao   +7 more
doaj   +1 more source

Role of Local and/or Metastasis-directed Therapy in Patients with Hormone-sensitive M1a Prostate Cancer:A Systematic Review [PDF]

, 2023
CONTEXT: It remains unclear whether men with hormone-sensitive prostate cancer (PCa) metastasized to nonregional lymph nodes (M1a) benefit from prostate-directed therapy (PDT) and/or metastasis-directed therapy (MDT).
Bergman, Andries M., Donswijk, Maarten L., Aluwini, Shafak, Droghetti, Matteo, de Barros, Hilda A., van Leeuwen, Pim J., Wilthagen, Erica A., van der Poel, Henk G., Özman, Oktay, van Moorselaar, R. Jeroen A., van Beurden, Isabeau   +10 more
core   +1 more source

RNA N1-methyladenosine regulator-mediated methylation modification patterns and heterogeneous signatures in glioma

Frontiers in Immunology, 2022
N1-methyladenosine (m1A) is ubiquitous in eukaryotic RNA and regulates mRNA translation. However, little is known about its regulatory role in glioma. Here, we identified 4 m1A modification-related patterns based on m1A regulators in the TCGA (The Cancer
Meng Mao, Meng Mao, Meng Mao, Qinjun Chu, Yongli Lou, Peipei Lv, Lin-jian Wang, Lin-jian Wang, Lin-jian Wang   +8 more
doaj   +1 more source