Results 61 to 70 of about 14,453 (241)

DataSheet_1_The m6A/m5C/m1A Regulated Gene Signature Predicts the Prognosis and Correlates With the Immune Status of Hepatocellular Carcinoma.docx [PDF]

open access: yes, 2022
RNA modification of m6A/m5C/m1A contributes to the occurrence and development of cancer. Consequently, this study aimed to investigate the functions of m6A/m5C/m1A regulated genes in the prognosis and immune microenvironment of hepatocellular carcinoma ...
De-An Mu (12959843)   +7 more
core   +1 more source

Monetarismo Más Allá del M1A [PDF]

open access: yes, 2004
Este trabajo analiza, desde un punto de vista empírico, la información que contiene el agregado M1A en Chile en comparación con la de otros agregados monetarios.
García, Pablo, Valdés, Rodrigo
core   +2 more sources

Identification of m1A/m6A/m5C/m7G-related genes and clusters associated with neuropathic pain. [PDF]

open access: yesFront Neurol
IntroductionRNA methylation modifications, including N1 methyladenosine (m1A), N6-methyladenosine (m6A), 5-methylcytosine (m5C), and 7-methylguanosine (m7G) methylation, have been increasingly implicated in nervous system disorders. The aim of this study
Tan L   +8 more
europepmc   +3 more sources

Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer’s disease

open access: yesHuman Molecular Genetics, 2021
AbstractRNA modifications affect many aspects of RNA metabolism and are involved in the regulation of many different biological processes. Mono-methylation of adenosine in the N1 position, N1-methyladensoine (m1A), is a reversible modification that is known to target rRNAs and tRNAs.
Andrew M Shafik   +4 more
openaire   +2 more sources

Role of Local and/or Metastasis-directed Therapy in Patients with Hormone-sensitive M1a Prostate Cancer:A Systematic Review [PDF]

open access: yes, 2023
CONTEXT: It remains unclear whether men with hormone-sensitive prostate cancer (PCa) metastasized to nonregional lymph nodes (M1a) benefit from prostate-directed therapy (PDT) and/or metastasis-directed therapy (MDT).
Bergman, Andries M.   +10 more
core   +1 more source

m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer

open access: yesTranslational Oncology, 2019
BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification.
Yueshui Zhao   +17 more
doaj   +1 more source

The Prognostic Value and Immune Landscapes of a m6A/m5C/m1A-Related LncRNAs Signature in Head and Neck Squamous Cell Carcinoma

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: N6-methyladenosine (m6A), 5-methylcytosine (m5C) and N1-methyladenosine (m1A) are the main RNA methylation modifications involved in the progression of cancer.
Enhao Wang   +7 more
doaj   +1 more source

RNA N1-methyladenosine regulator-mediated methylation modification patterns and heterogeneous signatures in glioma

open access: yesFrontiers in Immunology, 2022
N1-methyladenosine (m1A) is ubiquitous in eukaryotic RNA and regulates mRNA translation. However, little is known about its regulatory role in glioma. Here, we identified 4 m1A modification-related patterns based on m1A regulators in the TCGA (The Cancer
Meng Mao   +8 more
doaj   +1 more source

De-succinylation-induced accumulation of TRMT10C in the nucleus plays a detrimental role in coronary microembolization via its m1A modification function

open access: yesInternational Journal on Biological Sciences
Coronary microembolization (CME) refers to embolism in the coronary microcirculation. This study showed a reduction in succinyl transferase (CPT1A) and the succinylation substrate (succinyl-CoA) in cardiomyocytes in CME models, suppressing the ...
Chen-Kai Hu   +7 more
semanticscholar   +1 more source

The protective role of m1A during stress-induced granulation [PDF]

open access: yes, 2020
Post-transcriptional methylation of N6- and N1-adenine can effect transcriptome turnover and translation. Furthermore, the regulatory function of N6-methyladenine (m6A) during heat shock has been uncovered, including the enhancement of the phase ...
Alriquet, Marion   +12 more
core   +1 more source

Home - About - Disclaimer - Privacy