Results 81 to 90 of about 11,313 (179)

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, Volume 13, Issue 43, 3 August 2026.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Additional file 2 of m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA

Supplementary Material ...
Wang, Huan, Xie, Linjie, Guo, Haomin, Li, Lishi, Chen, Shuwei, Fan, Ye, Tian, Jingyuan, Xu, Liping, Kong, Xuejian, Xuan, Aiguo   +9 more
openaire   +1 more source

Extended field chemoradiation in M1a bladder carcinoma: A case report

Journal of Cancer Research and Therapeutics
ABSTRACT Currently, the recommended management in stage IVA bladder cancer is platinum-based chemotherapy followed by maintenance immunotherapy in those with no evidence of disease progression. Consolidative surgery may be considered in selected cases after chemotherapy.
Kannan, Periasamy, Shikha, Goyal, Santosh, Kumar, Vigneshwaran, Chandran, Rajender, Kumar   +4 more
openaire   +2 more sources

Comprehensive Pan‐Cancer Analysis of ABCA1: Insights From Multi‐Omics Data and Exploratory Validation in Esophageal Squamous Cell Carcinoma

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Cancer remains a major cause of global mortality, necessitating the identification of novel biomarkers to improve prognosis and guide therapy. ABCA1, an ATP‐binding cassette transporter involved in cholesterol efflux, has been implicated in tumorigenesis, yet its pan‐cancer roles and clinical relevance are not fully understood.
Chenyang Wang, Hanbing Wang, Xi Chen, Yingying Liu, Lili Duan, Zhenshun Li, Liaoran Niu, Aqiang Fan, Siyu Wei, Han Bai, Yujie Zhang, Wei Zhou, Jinqiang Liu, Wanli Yang, Yu Han, Liu Hong, Daiming Fan   +16 more
wiley   +1 more source

Epigenetic Regulation of Bone Homeostasis in Osteoporosis: Mechanisms, Evidence Gaps, and Translational Prospects

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Osteoporosis arises from an imbalance among osteoblast‐mediated bone formation, osteoclast‐mediated bone resorption, and osteocyte‐directed mechanosensory control, but the molecular events that connect aging, hormonal change, inflammation, and mechanical unloading to bone loss remain incompletely resolved.
Minjuan Du, Leisheng Wang
wiley   +1 more source

Validation of the mRNA epitranscriptome: SCARPET reveals that mapped m1A sites are inosine

EMBO Reports
A major goal in epitranscriptomics is to define the diversity of modified nucleotides in mRNA. Most candidate sites are discovered using transcriptome-wide mapping methods that rely on antibody enrichment or modification-induced misincorporations during ...
Rohit Nalavade, Aashiq H Mirza, Samie R Jaffrey   +2 more
doaj   +1 more source

Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)

International Journal of Cancer, Volume 159, Issue 3, Page 739-749, 1 August 2026.
What's New? Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...
Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group, Juliana Ababei, Jürgen Alt, Andreas Ammon, Sven Philip Aries, Akin Atmaca, Ivo Azeh, Eva‐Maria Barkowsky, Stefan Bauer, Silvan Becker, Dirk Behringer, Michael Bendel, Robin Benkelmann, Veronika Berberich, André Bethge, Annalen Bleckmann, Michael Boesche, Sabine Bohnet, Harald‐Robert Bruch, Wolfgang Brückl, Ulrike Burkhard‐Meier, Dieter Bürkle, Daniel C. Christoph, Petros Christopoulos, Peter Czyborra, Klaus‐Ulrich Däßler, Maike de Wit, Tobias Dechow, Reinhard Depenbusch, Karl‐Matthias Deppermann, Nicolas Dickgreber, Lutz Dietze, Markus Dommach, Steffen Dörfel, Wilfried Eberhardt, Ekkehard Eigendorff, Corinna Elender, Wolfgang Elsel, Till‐Oliver Emde, Bastian Eul, Martin Faehling, Florian Fauth, Thomas Fietz, Dimitri Flieger, Helmut Forstbauer, Werner Freier, Christian Frenzel, Florian Fuchs, Roswitha Fuchs, Thomas Fühner, Tobias Gaska, Wolfgang Gleiber, Tobias Graefe, Ullrich Graeven, Christian Grah, Sibylle Greiner, Frank Griesinger, Christian Grohé, Matthias Groschek, Carolin Groß‐Ophoff‐Müller, Andreas Günther, Sylvia Gütz, Siegfried Haas, Matthias Hackenthal, Volker Hagen, Carla Verena Hannig, Richard Hansen, Andrea Heider, David Heigener, Kathrin Heinrich, Natalia Heinz, Christiane Hering‐Schubert, Jörg Heßling, Conrad Heuchel, Petra Hoffknecht, Patricia Hortig, Gerdt Hübner, Horst‐Dieter Hummel, Ulrich Hutzschenreuter, Gerald Illerhaus, Thomas Illmer, Georg Innig, Melanie Janning, Jan Janssen, Christian Junghanß, Christian Kaes, Ulrich Kaiser, Stefan Kaldune, Haytham Kamal, Kato Kambartel, Lale Kayikci, Jens Kern, Dorothea Kingreen, Ortwin Klein, Konrad Kokowski, Wolfgang Körber, Dirk Koschel, Benoit Krämer, Beate Krammer‐Steiner, Jonas Kuon, Eckart Laack, Christof Lamberti, Markus Lehmann, Rumo David Leistner, Rüdiger Liersch, Hartmut Linde, Migle Link, Jörg Lipke, Verena Luber, Andreas Lück, Gita Maher, Kerstin Martin, Martin Metzenmacher, Christian Meyerzum Büschenfelde, Philipp Meyn, Enno Moorahrend, Christian Mozek, Annette Müller, Lothar Müller, Michael Neise, Holger Nückel, Arnd Nusch, Tobias Overbeck, Matthias Paland, Henning Pelz, Volker Petersen, Bettina Peuser, Christian Plate, Margarete Plath, Stefan Pluntke, Munir Rababah, Martin Reck, Niels Reinmuth, Marcel Reiser, Roland Repp, Daniel Reschke, Achim Rittmeyer, Yolanda Rodemer, Georg Rußwurm, Parvis Sadjadian, Reiner Sandner, Annette Sauer, Harald Schäfer, Clemens Schiefer, Burkhard Schmidt, Stephan Schmitz, Folker Schneller, Jan Schröder, Gunter Schuch, Christoph Schulz, Christian Schulz, Mathias Schulze, Christian Schumann, Wolfgang Schütte, Martin Schwaiblmair, Marcus Schweigert, Peter Florian Schwindt, Martin Sebastian, Bernd Seese, Gernot Seipelt, Christoph Sick, Theodoros Skentos, Thomas Sorgenfrei, Axel Stang, Johannes Steiff, Heike Steiniger, Susanne Stetter, Runa Stiegler, Heidrun Stumme, Amanda Tufman, Jens Uhlig, Ursula Vehling‐Kaiser, Gunther Vogel, Eyck von der Heyde, Oliver Waidmann, Cornelius F. Waller, Georg Weißenborn, Florian Weißinger, Martin Wermke, Claas Wesseler, Jörg Wiegand, Ute Wieschermann, Stefan Wilhelm, Jochen Wilke, Mark‐Oliver Zahn, Matthias Zaiss, Matthias Zeth, Joachim Zimber, Björn Schöttker   +207 more
wiley   +1 more source

The role of m5C, m1A and m7G modifications in tumors of urinary system

Frontiers in Cell and Developmental Biology
Malignant tumors of the urinary system, such as kidney cancer, bladder cancer, and prostate cancer, remain a significant challenge despite the various treatment options available. Identifying therapeutic targets for urological tumors is crucial due to the potential for recurrence and metastasis.
Wei Xue, Yuanyuan Zhao, Gong Zhang, Zhiyuan Li, Jixin Li, Xiang Fei   +5 more
openaire   +4 more sources

Towards an Integrated Staging Model for Bipolar Disorders: An International Society for Bipolar Disorders (ISBD) Staging Task Force Consensus Report

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives Three clinical staging models for bipolar disorder (BD) have been published, each with a different but complementary approach and focus. The International Society for Bipolar Disorders Staging Task Force aimed to integrate these models into one comprehensive three‐dimensional staging model, separately rating bipolar spectrum ...
Ralph Kupka, Danella Hafeman, Madeleine McCallum, Afra van der Markt, Hailey Tremain, Martin Alda, Jorge Almeida, Taiane de Azevedo Cardoso, Vicent Balanzá‐Martínez, Boris Birmaher, David J. Bond, Elisa Brietzke, Ines Chendo, Iria Grande, Tomas Hajek, Manon Hillegers, Marcia Kauer‐Sant'Anna, Rodrigo Mansur, Ives Cavalcante Passos, Ana Gonzalez Pinto, Robert Post, Mauricio Tohen, Gustavo Vazquez, Eduard Vieta, Lakshmi N. Yatham, Flávio Kapczinski, Michael Berk, Anne Duffy   +27 more
wiley   +1 more source

m1A-mediated regulation of BIRC2 mRNA stability drives apoptosis evasion and tumor progression in liver cancer

Cell Death and Disease
Liver cancer remains one of the leading causes of cancer-related mortality worldwide, with its progression driven by uncontrolled cell proliferation and evasion of apoptosis.
Yingmin Wu, Shenjie Zhang, Shilong Zhang, Jieyu Lu, Yuntao Yang, Zhirui Zeng, Shan Lei, Rui Mi, Yewei Zhang, Lichen Ge, Tengxiang Chen, Haiyang Li   +11 more
doaj   +1 more source