Results 101 to 110 of about 13,010 (203)
Frontiers in GeneticsIntroduction: Post-transcriptional RNA modifications are crucial regulators of tumor development and progression. In many biological processes, N1-methyladenosine (m1A) plays a key role.
Jian-jian Yin +10 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Cavitary lung lesions are commonly attributed to infection; however, malignancy should remain a diagnostic consideration. We report a 30‐year‐old non‐smoking man with a history of treated Hodgkin lymphoma who presented with a cavitary pulmonary adenocarcinoma. This case highlights the importance of considering rare malignant causes.
Hosam Aldalbahi, Nora Ahmed Bedaiwi
wiley +1 more source
Epigenetic modifications serve as crucial molecular switches for pathological fibrosis; howbeit the role of m1A in this condition remains enigmatic. Herein, it is found that ALKBH3 exerts a pro‐fibrotic effect in pathological skin fibrosis by reshaping ...
Shenying Luo +9 more
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1016-1026, October 2026.Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová +5 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley +8 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo +4 more
wiley +1 more source
, 2023 To investigate the prognostic value of N6-methyladenosine (m6A)-, 5-methylcytosine (m5C)-, and N1-methyladenosine (m1A)-related genes in cervical cancer (CESC) and predicting immunotherapy response. We downloaded cervical cancer mRNA expression profiles,
Jialei Zhu (5404505) +7 more
core +1 more source
Management of De Novo miN1 Prostate Cancer in the PSMA‐PET Era
The Prostate, Volume 86, Issue 14, Page 1404-1412, October 2026.ABSTRACT Background Prostate‐specific membrane antigen positron emission tomography (PSMA‐PET) is reshaping nodal staging in prostate cancer by detecting regional lymph node metastases with greater accuracy than conventional imaging. This has created a new cohort of patients with N1M0 disease detectable only on advanced imaging, raising important ...
Thomas McMaster +11 more
wiley +1 more source