Results 91 to 100 of about 11,313 (179)
AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids
We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos +5 more
wiley +1 more source
IntroductionColorectal cancer (CRC), characterized by its complex genetic heterogeneity and varied responses to treatment, is a leading cause of cancer-related mortality worldwide.
Lan Sun +6 more
doaj +1 more source
Examining the efficacy of a sanctuary to protect sharks in the Galapagos Marine Reserve
Abstract In 2016, Ecuador established a no‐take marine sanctuary in the northern portion of the Galapagos Marine Reserve (GMR), ostensibly to protect sharks. Arguably because of this, experimental longlining was permitted in the rest of the reserve as part of a compensation package to local fishers. Considering this agreement and very low bycatch rates
Leah R. Gerber +3 more
wiley +1 more source
Japanese Women's Attitudes Toward Learning Languages Other Than English in the Era of Global English
ABSTRACT This study on female Japanese learners of the Korean language is situated in the centuries‐long anti‐Korean sentiments in Japan, the global popularity of the Korean Wave, particularly among women, and the essentialized image of socially marginalized young Japanese women who study English with romantic desires for Western men.
Yoko Kobayashi
wiley +1 more source
Abstract An unusual chondritic xenolith was found in two sequentially prepared thin sections of a sample from the Krymka (LL3.2) chondrite. The xenolith has a rounded, slightly deformed shape of about 5 mm in apparent diameter and is partially surrounded by a double rim made of an inner fine‐grained silicate‐rich rim and an outer sulfide‐rich rim.
Aelita Girich +6 more
wiley +1 more source
Dinoflagellate mRNA is pervasively modified with m1A
N(1)-methyladenosine (m(1)A) is a very rare RNA modification in mammalian mRNA, which occurs in sequences resembling the T-loop of tRNAs and may not have significant effects on gene expression. A new study in this issue now reports that m(1)A is abundant and dynamic in the 3′UTR of mRNAs of dinoflagellates, and could have an important role in post ...
Jianheng Fox Liu, Samie R Jaffrey
openaire +2 more sources
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide, with hepatitis B virus (HBV) infection being the major risk factor. Dysregulation of mRNA methylation contributes to tumorigenesis and virus replication. However, the association of N1‐
Rui Zhang +12 more
doaj +1 more source
m6A/m1A/m5C-Associated Methylation Alterations and Immune Profile in MDD
AbstractMajor depressive disorder (MDD) is a prevalent psychiatric condition often accompanied by severe impairments in cognitive and functional capacities. This research was conducted to identify RNA modification-related gene signatures and associated functional pathways in MDD. Differentially expressed RNA modification-related genes in MDD were first
Xin Ren +9 more
openaire +2 more sources
P2.01-074 Wait and See: A Favorable Alternative for R-M1a and S-M1a NSCLC Patients [PDF]
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