Results 91 to 100 of about 13,010 (203)
Nature Communications, 2021 Metabolic adaptation has been reported to promote cancer, yet the underlying mechanisms are not clear. Here, the authors show that m1A methylation in tRNA regulates cholesterol metabolism in liver cancer stem cells and m1A inhibition decreases ...
Yanying Wang +12 more
doaj +1 more source
Everyday Stressors and Sense of Purpose: The Role of Stressor‐Related Opportunities for Goal Pursuit
Journal of Personality, EarlyView.ABSTRACT Objective This study examined whether everyday stressor occurrence is associated with lower sense of purpose, and whether this association depends on stressor‐related goal opportunities, the Big Five personality traits, or trait purpose. Methods Data came from the Daily Experiences and Health Study (N = 236, ages 25–87).
Mart Visser +5 more
wiley +1 more source
HeliyonN1-methyladenosine (m1A) modification is a crucial post-transcriptional regulatory mechanism of messenger RNA (mRNA) in living organisms. Few studies have focused on analysis of m1A regulators in lower-grade gliomas (LGG). We employed the Nonnegative Matrix Factorization (NMF) technique on The Cancer Genome Atlas (TCGA) dataset to categorize LGG ...
Kunjian Lei +16 more
openaire +3 more sources
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
Journal of Periodontal Research, EarlyView.This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Obesity Reviews, EarlyView.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang +4 more
wiley +1 more source
Population and Development Review, EarlyView.Abstract One in four young mothers in Latin America raises her children without a partner, yet more than two‐thirds do so within extended households, typically with their own parents. Despite the social implications of single‐parent families, it remains unclear to what extent the prevalence and living arrangements of single mothers have evolved over ...
Federica Becca +2 more
wiley +1 more source
This work analyzes, from an empirical standpoint, the information contained in the M1A aggregate in Chile and compares it with other aggregates. The findings reveal that, at least for now, the M1A aggregate does not seem to have particularly valuable ...
Pablo García,, Rodrigo O. Valdés
core
Journal of Fish Diseases, Volume 49, Issue 11, November 2026.ABSTRACT Vibrio harveyi is an important bacterial pathogen in marine aquaculture, responsible for outbreaks affecting a wide range of fish species. Early detection of potentially virulent isolates in fish and environmental samples is essential for effective disease prevention and management, particularly under field conditions where the pathogen may be
Javier Barriga‐Cuartero +4 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
, 2021 Background: N6-methyladenosine (m6A), 5-methylcytosine (m5C) and N1-methyladenosine (m1A) are the main RNA methylation modifications involved in the progression of cancer.
Ruijie Ming (5483864) +7 more
core +1 more source