Results 91 to 100 of about 11,313 (179)

AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids

open access: yesBiology of the Cell, Volume 118, Issue 8, August 2026.
We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos   +5 more
wiley   +1 more source

Identification and functional characterization of m1A-related genes in colorectal cancer: implications for prognosis, immune infiltration, and therapeutic strategies

open access: yesFrontiers in Oncology
IntroductionColorectal cancer (CRC), characterized by its complex genetic heterogeneity and varied responses to treatment, is a leading cause of cancer-related mortality worldwide.
Lan Sun   +6 more
doaj   +1 more source

Examining the efficacy of a sanctuary to protect sharks in the Galapagos Marine Reserve

open access: yesConservation Science and Practice, Volume 8, Issue 8, August 2026.
Abstract In 2016, Ecuador established a no‐take marine sanctuary in the northern portion of the Galapagos Marine Reserve (GMR), ostensibly to protect sharks. Arguably because of this, experimental longlining was permitted in the rest of the reserve as part of a compensation package to local fishers. Considering this agreement and very low bycatch rates
Leah R. Gerber   +3 more
wiley   +1 more source

Japanese Women's Attitudes Toward Learning Languages Other Than English in the Era of Global English

open access: yesInternational Journal of Applied Linguistics, Volume 36, Issue 3, Page 2298-2308, August 2026.
ABSTRACT This study on female Japanese learners of the Korean language is situated in the centuries‐long anti‐Korean sentiments in Japan, the global popularity of the Korean Wave, particularly among women, and the essentialized image of socially marginalized young Japanese women who study English with romantic desires for Western men.
Yoko Kobayashi
wiley   +1 more source

Origin and formation of a chondritic xenolith in Krymka (LL3.2, breccia): Indications for a late formation of the accretionary breccia

open access: yesMeteoritics &Planetary Science, Volume 61, Issue 8, Page 2016-2047, August 2026.
Abstract An unusual chondritic xenolith was found in two sequentially prepared thin sections of a sample from the Krymka (LL3.2) chondrite. The xenolith has a rounded, slightly deformed shape of about 5 mm in apparent diameter and is partially surrounded by a double rim made of an inner fine‐grained silicate‐rich rim and an outer sulfide‐rich rim.
Aelita Girich   +6 more
wiley   +1 more source

Dinoflagellate mRNA is pervasively modified with m1A

open access: yesEMBO Reports
N(1)-methyladenosine (m(1)A) is a very rare RNA modification in mammalian mRNA, which occurs in sequences resembling the T-loop of tRNAs and may not have significant effects on gene expression. A new study in this issue now reports that m(1)A is abundant and dynamic in the 3′UTR of mRNAs of dinoflagellates, and could have an important role in post ...
Jianheng Fox Liu, Samie R Jaffrey
openaire   +2 more sources

TRMT6‐Mediated m1A Modification of CDK9 mRNA is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide, with hepatitis B virus (HBV) infection being the major risk factor. Dysregulation of mRNA methylation contributes to tumorigenesis and virus replication. However, the association of N1‐
Rui Zhang   +12 more
doaj   +1 more source

m6A/m1A/m5C-Associated Methylation Alterations and Immune Profile in MDD

open access: yesMolecular Neurobiology
AbstractMajor depressive disorder (MDD) is a prevalent psychiatric condition often accompanied by severe impairments in cognitive and functional capacities. This research was conducted to identify RNA modification-related gene signatures and associated functional pathways in MDD. Differentially expressed RNA modification-related genes in MDD were first
Xin Ren   +9 more
openaire   +2 more sources

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