Results 111 to 120 of about 13,010 (203)
Pulmonary Circulation, Volume 16, Issue 4, October 2026.ABSTRACT Idiopathic pulmonary arterial hypertension (IPAH) is a pulmonary vascular disease with a poor prognosis. Its pathogenesis remains unclear and the treatment methods are limited. The expression of tRNA‐derived small RNA (tsRNA) in IPAH tissues remains unknown. tsRNA sequencing was conducted on lung tissue samples obtained from patients with IPAH
Yuan Chen +7 more
wiley +1 more source
Ablative radiotherapy in castration‐resistant prostate cancer
BJU International, Volume 138, Issue 4, Page 659-665, October 2026.Objective To prove the oncological benefit of ablative radiotherapy in patients with up to five metastases from castration‐resistant prostate cancer (CRPC) a single‐centre randomised trial was initiated. Patients and Methods This monocentric, randomised, phase II clinical trial enrolled patients with up to five prostate‐specific membrane antigen ...
Tobias Hölscher +9 more
wiley +1 more source
N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer’s disease [PDF]
One mechanism of particular interest to regulate mRNA fate post-transcriptionally is mRNA modification. Especially the extent of m1A mRNA methylation is highly discussed due to methodological differences. However, one single m1A site in mitochondrial ND5
Wirtz Martin, Katja M. +18 more
core +1 more source
Polyphenism Through RNA Chemical Modifications
Molecular Ecology, Volume 35, Issue 19, October 2026.ABSTRACT Polyphenism, the capacity of a single genotype to produce discrete phenotypes in response to environmental cues, has long served as a model for understanding developmental plasticity. While classical studies have highlighted hormonal signalling and transcription‐factor‐driven gene regulatory networks that mediate these environmentally induced ...
Ralf Schneider, Ehsan Pashay Ahi
wiley +1 more source
Extended field chemoradiation in M1a bladder carcinoma: A case report
Journal of Cancer Research and TherapeuticsABSTRACT Currently, the recommended management in stage IVA bladder cancer is platinum-based chemotherapy followed by maintenance immunotherapy in those with no evidence of disease progression. Consolidative surgery may be considered in selected cases after chemotherapy.
Kannan, Periasamy +4 more
openaire +2 more sources
m1A, m5C, m6A genes and angiogenesis-related mRNAs.
m1A, m5C, m6A genes and angiogenesis-related mRNAs.
Ruixiu Chen (17782446) +8 more
core +1 more source
Prostate-directed radiation therapy and overall survival for men with M1a prostate cancer
, 2020 101 Background: A recent randomized controlled trial demonstrated that radiation therapy to the prostate improves overall survival for men with newly diagnosed metastatic prostate cancer with a low metastatic burden.
Mahal, Brandon Arvin Virgil +8 more
core +1 more source
The role of m5C, m1A and m7G modifications in tumors of urinary system
Frontiers in Cell and Developmental BiologyMalignant tumors of the urinary system, such as kidney cancer, bladder cancer, and prostate cancer, remain a significant challenge despite the various treatment options available. Identifying therapeutic targets for urological tumors is crucial due to the potential for recurrence and metastasis.
Wei Xue +5 more
openaire +4 more sources
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase
, 2004 The modified nucleoside 1-methyladenosine (m1A) is found in the T-loop of many tRNAs from organisms belonging to the three domains of life (Eukaryota, Bacteria, Archaea).
Bujnicki, Janusz M. +8 more
core +1 more source