Results 111 to 120 of about 14,453 (241)

Prostate-directed radiation therapy and overall survival for men with M1a prostate cancer [PDF]

, 2020
101 Background: A recent randomized controlled trial demonstrated that radiation therapy to the prostate improves overall survival for men with newly diagnosed metastatic prostate cancer with a low metastatic burden.
Mahal, Brandon Arvin Virgil, Nguyen, Paul L, King, Martin T, Muralidhar, Vinayak, Mouw, Kent William, Butler, Santino, Orio, Peter F, Yang, David Dewei, Martin, Neil E   +8 more
core   +1 more source

tRNA-m1A methylation controls the infection of Magnaporthe oryzae by supporting ergosterol biosynthesis.

Developmental Cell
Ergosterols are essential components of fungal plasma membranes. Inhibitors targeting ergosterol biosynthesis (ERG) genes are critical for controlling fungal pathogens, including Magnaporthe oryzae, the fungus that causes rice blast.
Rongrong He, Ziwei Lv, Yinan Li, Shuchao Ren, Jiaqi Cao, Jun Zhu, Xinrong Zhang, Huimin Wu, Lihao Wan, Ji Tang, Shutong Xu, Xiao-Lin Chen, Zhipeng Zhou   +12 more
semanticscholar   +1 more source

Comprehensive analyses of m1A regulator-mediated modification patterns determining prognosis in lower-grade glioma (running title: m1A in LGG)

Heliyon
N1-methyladenosine (m1A) modification is a crucial post-transcriptional regulatory mechanism of messenger RNA (mRNA) in living organisms. Few studies have focused on analysis of m1A regulators in lower-grade gliomas (LGG). We employed the Nonnegative Matrix Factorization (NMF) technique on The Cancer Genome Atlas (TCGA) dataset to categorize LGG ...
Kunjian Lei, Yilei Sheng, Min Luo, Junzhe Liu, Chuandong Gong, Shigang Lv, Wei Tu, Minhua Ye, Miaojing Wu, Bing xiao, Hua Fang, Haitao Luo, Xinjun Liu, Xiaoyan Long, Xingen Zhu, Kai Huang, Jingying Li   +16 more
openaire   +3 more sources

Loud and Clear Epitranscriptomic m1A Signals: Now in Single-Base Resolution [PDF]

Molecular Cell, 2017
In this issue of Molecular Cell, Li et al. (2017) map N1-methyladenosine (m1A) with base precision, parsing the methylome into subsets differing in location, sequence-structure features, and catalyzing enzymes, thereby aiding functional investigation.
Dominissini, Dan, Rechavi, Gideon
openaire   +2 more sources

Everyday Stressors and Sense of Purpose: The Role of Stressor‐Related Opportunities for Goal Pursuit

Journal of Personality, EarlyView.
ABSTRACT Objective This study examined whether everyday stressor occurrence is associated with lower sense of purpose, and whether this association depends on stressor‐related goal opportunities, the Big Five personality traits, or trait purpose. Methods Data came from the Daily Experiences and Health Study (N = 236, ages 25–87).
Mart Visser, Lydia Q. Ong, Anita DeLongis, Patrick L. Hill, Nancy L. Sin, Patrick Klaiber   +5 more
wiley   +1 more source

m1A, m5C, m6A genes and angiogenesis-related mRNAs. [PDF]

m1A, m5C, m6A genes and angiogenesis-related mRNAs.
Ruixiu Chen (17782446), Xinying Zheng (12000590), Lihua Du (4432621), Shiwei Duan (112890), Qibin Yan (9188996), Jinze Shen (14293010), Qing Xia (114230), Qurui Wang (14293013), Hanbing Li (3841237)   +8 more
core   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Origin and formation of a chondritic xenolith in Krymka (LL3.2, breccia): Indications for a late formation of the accretionary breccia

Meteoritics &Planetary Science, EarlyView.
Abstract An unusual chondritic xenolith was found in two sequentially prepared thin sections of a sample from the Krymka (LL3.2) chondrite. The xenolith has a rounded, slightly deformed shape of about 5 mm in apparent diameter and is partially surrounded by a double rim made of an inner fine‐grained silicate‐rich rim and an outer sulfide‐rich rim.
Aelita Girich, Addi Bischoff, Samuel Ebert, Kazuhide Nagashima, Andreas Morlok, Harald Hiesinger, Jasper Berndt   +6 more
wiley   +1 more source

A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase [PDF]

, 2004
The modified nucleoside 1-methyladenosine (m1A) is found in the T-loop of many tRNAs from organisms belonging to the three domains of life (Eukaryota, Bacteria, Archaea).
Bujnicki, Janusz M., Wouters, Johan, Stalon, Victor, Grosjean, Henri, Roovers, Martine, Wouters, Johan; id_orcid, Tricot, Catherine, Droogmans, Louis, Bujnicki, Janusz Marek   +8 more
core   +1 more source

The Living Arrangements of Single Mothers in Latin America: Stratification by Education and Partnership Status

Population and Development Review, EarlyView.
Abstract One in four young mothers in Latin America raises her children without a partner, yet more than two‐thirds do so within extended households, typically with their own parents. Despite the social implications of single‐parent families, it remains unclear to what extent the prevalence and living arrangements of single mothers have evolved over ...
Federica Becca, Diego Alburez‐Gutierrez, Albert Esteve   +2 more
wiley   +1 more source